Psycho-Babble Medication Thread 102528

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Zoloft: Physiological Reactions

Posted by Pokey on April 9, 2002, at 13:37:52

The first day of taking Zoloft several years ago I noticed physiological reactions within a few hours. I went off the drug and now I am back on it. The first day I had the same reaction as I did several years ago. Most people only experience these reactions after the drug has been in their system for several weeks. My question is: Aside from the usual side effects of diarrhea, nausea, inability to sleep, etc., which occur in the first few weeks of taking Zoloft, has anyone else noticed physiological reactions such as pupil dilation, heightened sensory perception to environmental stimuli, and increased alertness ON THE VERY FIRST DAY of taking Zoloft? Is this a normal reaction or does it tell me something about my brain chemistry that I really should know?

 

Re: Zoloft: Physiological Reactions » Pokey

Posted by TSA West on April 9, 2002, at 16:11:43

In reply to Zoloft: Physiological Reactions, posted by Pokey on April 9, 2002, at 13:37:52

You just have extreme sensitivity to that particular medication. I doubt that you would have the same reaction to the purer, cleaner SSRI Celexa. Celexa tends to help people sleep--in contrast to yours and other patients' experiences with Zoloft.

 

Re: Zoloft: Physiological Reactions

Posted by rainbowlight on April 9, 2002, at 18:57:19

In reply to Zoloft: Physiological Reactions, posted by Pokey on April 9, 2002, at 13:37:52

Hi Pokey. I am on my 4th(?) day of starting Zoloft, 25 mgs. once a day. I noticed changes on the first day. I was much calmer and my OCD wasn't as bad (which is what I am taking it for). I am very med sensitive and I can usually figure out if a med is going to be the one for me within a week. Some people, including the pdocs think this is impossible, but I have found it to be true for me. The only side effects I have had are slight nausea and feeling sleepy early in the night (I take the med in the morning).

 

Re: Zoloft: Physiological Reactions

Posted by katekite on April 10, 2002, at 9:38:00

In reply to Re: Zoloft: Physiological Reactions, posted by rainbowlight on April 9, 2002, at 18:57:19

I have heard of paradoxical transient worsening of symptoms at the beginning of ssris. Supposedly should pass.

I'd like to second the opinion about being able to sense some of the beneficial effects of ssris within the first week. Not with all ssris, but certainly with Paxil (which I can take as a sleep aid on a once in a while basis, a couple hours after I take it the warm fuzzy content feeling sets in as if I had just finished Thanksgiving dinner and some ice cream, which is not mere sedation). Has a bad hangover the following day though, there are cleaner sleep aids.

Kate


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