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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by NikkiT2 on February 14, 2002, at 15:51:43
Finally found some DLPA.. they're 500mg tablets. The label says one tablet daily..
Any advice on this??
Nikki
Posted by paulb on February 14, 2002, at 17:31:04
In reply to DL-Phenylalanine - dose??, posted by NikkiT2 on February 14, 2002, at 15:51:43
> Finally found some DLPA.. they're 500mg tablets. The label says one tablet daily..
>
> Any advice on this??
>
> NikkiDL Phenylalanine was very useful for me Nikki although I found L-Tyrosine to be more effective. Im sure you know that they both are precursors to the catecholamines dopamine and norepinephrine. I can say a few things about DL Phenylalanine and L-Tyrosine. They are more consistent if taken on an empty stomach. First thing in the morning is a good time. It can be a trial and error process. Too much is as useless as not enough because the norepinephrine and dopamine receptors will up-regulate or/and the auto-receptors that control the release of these neurotransmitters will cease firing as much neurotransmitter because there is too much. A balance has to be found.
I would take a good B-Vitamin. Folic acid and B6 are very important. Vitamin C, Magnesium and Calcium also support the synthesis of neurotransmitters. As I recommended to you before SAM-E is excellent for the synthesis of neurotransmitters. I think DL-Phenylanine is okay with re-uptake inhibitors although I found that I wasnt able to get a response. I suspect the amino acid prevented the AD from working[5-HTP and Paroxetine]. You may want to consider this. A little could boost an AD's effect significantly. Bear in mind if a depressed person is given an antidepressant without any augmentation it will still take a few weeks to start working and will often been effective for a long time.
I would add that the catecholamines are implicated in maintaining drive and energy so might be particulaly useful. Let us know how it work out.
Paulb
Posted by NikkiT2 on February 14, 2002, at 18:44:18
In reply to Re: DL-Phenylalanine - dose??, posted by paulb on February 14, 2002, at 17:31:04
I'm taing Vit B12 too.. and am actually in processof coming off my AD (effexor), so will be left with just and anti-psychotic (Zyprexa)... I'll take it first thing in morning and see how it goes..
ta for all that info!!
Nikki x
Posted by Frankie on February 15, 2002, at 12:24:52
In reply to Re: DL-Phenylalanine - dose??, posted by paulb on February 14, 2002, at 17:31:04
> > Finally found some DLPA.. they're 500mg tablets. The label says one tablet daily..
> >
> > Any advice on this??
> >
> > Nikki
>
> DL Phenylalanine was very useful for me Nikki although I found L-Tyrosine to be more effective. Im sure you know that they both are precursors to the catecholamines dopamine and norepinephrine. I can say a few things about DL Phenylalanine and L-Tyrosine. They are more consistent if taken on an empty stomach. First thing in the morning is a good time. It can be a trial and error process. Too much is as useless as not enough because the norepinephrine and dopamine receptors will up-regulate or/and the auto-receptors that control the release of these neurotransmitters will cease firing as much neurotransmitter because there is too much. A balance has to be found.
>
> I would take a good B-Vitamin. Folic acid and B6 are very important. Vitamin C, Magnesium and Calcium also support the synthesis of neurotransmitters. As I recommended to you before SAM-E is excellent for the synthesis of neurotransmitters. I think DL-Phenylanine is okay with re-uptake inhibitors although I found that I wasnt able to get a response. I suspect the amino acid prevented the AD from working[5-HTP and Paroxetine]. You may want to consider this. A little could boost an AD's effect significantly. Bear in mind if a depressed person is given an antidepressant without any augmentation it will still take a few weeks to start working and will often been effective for a long time.
>
> I would add that the catecholamines are implicated in maintaining drive and energy so might be particulaly useful. Let us know how it work out.
> PaulbPaul,
What would help me overcome the lethargy of the SSRI's, including low motivation, but would not increase my OCD problems? I have some L-tyrosine on hand, but Ritalin made my mind out of control with obsessiveness. I'd rather just add a few natural supplements instead of more drugs. Thanks.
Frankie.
Posted by JohnX2 on February 15, 2002, at 17:43:15
In reply to DL-Phenylalanine - dose??, posted by NikkiT2 on February 14, 2002, at 15:51:43
Hi Nikki,In most areas of the brain the thing that limits
the production of dopamine and norepinephrine
is something called tyrosine hydroxylase. This
is an enzyme that converts the amino acid
into the brain chemical. Generally the diet
alone already saturates the enyme, but you
can give the amino acid a shot. Some people have
felt a benifit in the 500-2000 mg range. You need
to take good b vitamins for it to work. Good luck.-John
> Finally found some DLPA.. they're 500mg tablets. The label says one tablet daily..
>
> Any advice on this??
>
> Nikki
Posted by 3 Beer Effect on February 16, 2002, at 2:59:26
In reply to DL-Phenylalanine - dose??, posted by NikkiT2 on February 14, 2002, at 15:51:43
>dl-phenylalanine may be somewhat helpful if you have chronic pain because it inhibits the breakdown of the body's natural painkillers.
Otherwise, for depression or as a stimulant, l-phenylalanine will work better because it crosses the blood brain barrier much easier. After a week or two at 1500 mg/morning, I started to notice a stimulant effect. (I have had success with Twinlab, but not w/ Bluebonnet or Country Life brands).
The normal dosages for L-phenylalanine or L-Tyrosine is 500 to 1500 gm per day. I have read books that recommend ridiculous amounts of these amino acids but no one knows if high dose aminos can cause long term effects/damage.
The problem with L-Tyrosine is that it does not cross the blood brain barrier & so is dependent & competes with other amino acids/proteins for uptake into the brain through a carrier that is already saturated by a normal diet. There is a form called n-acetyl-L-tyrosine that seems to be much bioavailable than L-tyrosine & would probably work better. N-acetyl-L-Tyrosine is relatively harder to find, but you could definitely find it on the internet. I am trying to find a good book/source on amino acid psychopharmacology but I have had a very difficult time finding unbiased info about amino acids online, or in bookstores. Most of the sites providing the amino acid research information also sell amino acids!
3 Beers.
Posted by spike4848 on February 16, 2002, at 4:24:10
In reply to l-phenylalanine penetrates BBB better, posted by 3 Beer Effect on February 16, 2002, at 2:59:26
Posted by 3 Beer Effect on February 16, 2002, at 15:01:39
In reply to Welcome Home 3 Beer Effect (nm), posted by spike4848 on February 16, 2002, at 4:24:10
This is the end of the thread.
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