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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Anna P. on October 1, 2001, at 12:28:38
I plan on trying Nimodipine. I'm currently on:
Lithium, Trilafon and Reboxetine.
Are there any drug interactions if I add Nimodipine to my combination?Anna P.
Posted by SalArmy4me on October 1, 2001, at 15:43:36
In reply to Nimodipine interactions, posted by Anna P. on October 1, 2001, at 12:28:38
Where did you buy the Nimodipine from? I'm curious.
> I plan on trying Nimodipine. I'm currently on:
> Lithium, Trilafon and Reboxetine.
> Are there any drug interactions if I add Nimodipine to my combination?
>
> Anna P.
Posted by Anna P. on October 1, 2001, at 16:30:44
In reply to Re: Nimodipine interactions » Anna P., posted by SalArmy4me on October 1, 2001, at 15:43:36
> Where did you buy the Nimodipine from? I'm curious.
> I've got it by presciption from Europe, but the
doctor doesn't know about the interactions since
he doesn't use it often.Anna P.
> > I plan on trying Nimodipine. I'm currently on:
> > Lithium, Trilafon and Reboxetine.
> > Are there any drug interactions if I add Nimodipine to my combination?
> >
> > Anna P.
Posted by bob on October 1, 2001, at 17:31:41
In reply to Nimodipine interactions, posted by Anna P. on October 1, 2001, at 12:28:38
> I plan on trying Nimodipine. I'm currently on:
> Lithium, Trilafon and Reboxetine.
> Are there any drug interactions if I add Nimodipine to my combination?
>
> Anna P.*****************
I'll try this again, since it seems like my first endeavor failed to post.
What is Nimodipine, and what is it commonly used for? Is it new?
Bob
Posted by Anna P. on October 2, 2001, at 15:52:25
In reply to Re: Nimodipine interactions, posted by bob on October 1, 2001, at 17:31:41
> > I plan on trying Nimodipine. I'm currently on:
> > Lithium, Trilafon and Reboxetine.
> > Are there any drug interactions if I add Nimodipine to my combination?
> >
> > Anna P.
>
> *****************
>
> I'll try this again, since it seems like my first endeavor failed to post.
>
> What is Nimodipine, and what is it commonly used for? Is it new?
>
> Nimodipine is the calcium channel blocker that is prescribed as the last resort when everything else fails. It's supposed to have the energizing
effect. It's used mostly by NIMH.Anna P.
Posted by bob on October 2, 2001, at 19:43:38
In reply to Re: Nimodipine/bob, posted by Anna P. on October 2, 2001, at 15:52:25
> > > I plan on trying Nimodipine. I'm currently on:
> > > Lithium, Trilafon and Reboxetine.
> > > Are there any drug interactions if I add Nimodipine to my combination?
> > >
> > > Anna P.
> >
> > *****************
> >
> > I'll try this again, since it seems like my first endeavor failed to post.
> >
> > What is Nimodipine, and what is it commonly used for? Is it new?
> >
> > Nimodipine is the calcium channel blocker that is prescribed as the last resort when everything else fails. It's supposed to have the energizing
> effect. It's used mostly by NIMH.
>
> Anna P.
Anna:I thought Topomax was supposed to have an energizing effect also? Why is Nimodipine considered a "last resort"? Is it dangerous?
Posted by Anna P. on October 2, 2001, at 20:07:34
In reply to Re: Nimodipine/bob, posted by bob on October 2, 2001, at 19:43:38
> > > > I plan on trying Nimodipine. I'm currently on:
> > > > Lithium, Trilafon and Reboxetine.
> > > > Are there any drug interactions if I add Nimodipine to my combination?
> > > >
> > > > Anna P.
> > >
> > > *****************
> > >
> > > I'll try this again, since it seems like my first endeavor failed to post.
> > >
> > > What is Nimodipine, and what is it commonly used for? Is it new?
> > >
> > > Nimodipine is the calcium channel blocker that is prescribed as the last resort when everything else fails. It's supposed to have the energizing
> > effect. It's used mostly by NIMH.
> >
> > Anna P.
>
>
> Anna:
>
> I thought Topomax was supposed to have an energizing effect also? Why is Nimodipine considered a "last resort"? Is it dangerous?
Bob,I already tried Topomax, Neurontin and Lamictal
so I'm out of choices. Myself, I'm looking for more info about Nimodipine, as it is rare prescribed. Means, I haven't met anyone on this board who takes it.Anna P.
Posted by bob on October 2, 2001, at 22:28:37
In reply to Re: Nimodipine/bob, posted by Anna P. on October 2, 2001, at 20:07:34
> > > > > I plan on trying Nimodipine. I'm currently on:
> > > > > Lithium, Trilafon and Reboxetine.
> > > > > Are there any drug interactions if I add Nimodipine to my combination?
> > > > >
> > > > > Anna P.
> > > >
> > > > *****************
> > > >
> > > > I'll try this again, since it seems like my first endeavor failed to post.
> > > >
> > > > What is Nimodipine, and what is it commonly used for? Is it new?
> > > >
> > > > Nimodipine is the calcium channel blocker that is prescribed as the last resort when everything else fails. It's supposed to have the energizing
> > > effect. It's used mostly by NIMH.
> > >
> > > Anna P.
> >
> >
> > Anna:
> >
> > I thought Topomax was supposed to have an energizing effect also? Why is Nimodipine considered a "last resort"? Is it dangerous?
>
>
> Bob,
>
> I already tried Topomax, Neurontin and Lamictal
> so I'm out of choices. Myself, I'm looking for more info about Nimodipine, as it is rare prescribed. Means, I haven't met anyone on this board who takes it.
>
> Anna P.Anna:
What types of failures were the trials with the other CCBs? Were they situations where the drugs didn't do much of anything, or were they failures because of unwanted and intolerable effects?
Bob
Posted by Anna P. on October 3, 2001, at 9:21:30
In reply to Re: Nimodipine/bob, posted by bob on October 2, 2001, at 22:28:37
> > > > > > I plan on trying Nimodipine. I'm currently on:
> > > > > > Lithium, Trilafon and Reboxetine.
> > > > > > Are there any drug interactions if I add Nimodipine to my combination?
> > > > > >
> > > > > > Anna P.
> > > > >
> > > > > *****************
> > > > >
> > > > > I'll try this again, since it seems like my first endeavor failed to post.
> > > > >
> > > > > What is Nimodipine, and what is it commonly used for? Is it new?
> > > > >
> > > > > Nimodipine is the calcium channel blocker that is prescribed as the last resort when everything else fails. It's supposed to have the energizing
> > > > effect. It's used mostly by NIMH.
> > > >
> > > > Anna P.
> > >
> > >
> > > Anna:
> > >
> > > I thought Topomax was supposed to have an energizing effect also? Why is Nimodipine considered a "last resort"? Is it dangerous?
> >
> >
> > Bob,
> >
> > I already tried Topomax, Neurontin and Lamictal
> > so I'm out of choices. Myself, I'm looking for more info about Nimodipine, as it is rare prescribed. Means, I haven't met anyone on this board who takes it.
> >
> > Anna P.
>
> Anna:
>
> What types of failures were the trials with the other CCBs? Were they situations where the drugs didn't do much of anything, or were they failures because of unwanted and intolerable effects?
>
> BobBob,
There was even something worse - drug pooped out
after some time of working.Anna P.
Posted by SLS on October 6, 2001, at 18:24:51
In reply to Nimodipine interactions, posted by Anna P. on October 1, 2001, at 12:28:38
> I plan on trying Nimodipine. I'm currently on:
> Lithium, Trilafon and Reboxetine.
> Are there any drug interactions if I add Nimodipine to my combination?
>
> Anna P.Oops. I thought I submitted a post here yesterday. I probably forgot to confirm it. Maybe it was along another thread. Anyway, the only drug interaction that I can think of that might be important is the combined blood-pressure lowering effects of nimodipine and Trilafon (perphenazine).
- Scott
Posted by Sunnely on October 7, 2001, at 22:48:00
In reply to Nimodipine interactions, posted by Anna P. on October 1, 2001, at 12:28:38
> I plan on trying Nimodipine. I'm currently on:
> Lithium, Trilafon and Reboxetine.
> Are there any drug interactions if I add Nimodipine to my combination?
>
> Anna P.*********************
Nimodipine (Nimotop) belongs in the class of calcium channel blockers (CCBs). The combined use of a CCB such as verapmil (Calan, Verelan) and dilitiazem (Cardizem, Tiazac, Dilacor) had been reported to cause unpredictable increase or decrease in lithium effect. The exact mechanism is unknown. It is clinically prudent to check the lithium level prior to and a few days after adding nimodipine to lithium.
There have been rare reports of neurotoxicity with the combined use of lithium and verapamil as this CCB crosses the blood-brain barrier. Also, there were some reports of cardiotoxicity with the combined use of lithium and verapamil. The exact mechanism is unknown.
Nimodipine itself has a considerable effect on the cerebral ( brain) arteries. Lithium itself can cause heart effects including slowing of the heart rate (bradycardia) and even heart block.
I don't know if these reported adverse effects with the combined use of verapamil (and diltiazem) and lithium have been reported with the combination of nimodipine and lithium. It will be clinically prudent to do an electrocardiogram first before combining the two and periodically during treatment.
This is the end of the thread.
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