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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Geraldo macias on March 26, 2001, at 20:52:39
I have been on effexxor xr 75 for about 1 year.
The medicine has been very effective for dealing with anger control due to depression. However I have noticed sexual side effects. I have noticed a decreased desire to have sex. No problems with erection and sex is still often on my mind, but, the actual act of having sex I could take it or leave it.
Once engaged in sex, The medicine seems to give me increased staying power, but the orgasms seem less intense. Has anyone else experienced this. Is there another medicine that I could make a transition to?
Posted by Bill L on March 27, 2001, at 9:07:54
In reply to sexual side effects, posted by Geraldo macias on March 26, 2001, at 20:52:39
Most people on antidepressants experience sexual side effects worse than yours. Consider yourself lucky and stay on your current medication!
> I have been on effexxor xr 75 for about 1 year.
> The medicine has been very effective for dealing with anger control due to depression. However I have noticed sexual side effects. I have noticed a decreased desire to have sex. No problems with erection and sex is still often on my mind, but, the actual act of having sex I could take it or leave it.
> Once engaged in sex, The medicine seems to give me increased staying power, but the orgasms seem less intense. Has anyone else experienced this. Is there another medicine that I could make a transition to?
Posted by jb on March 29, 2001, at 9:14:00
In reply to Re: sexual side effects, posted by Bill L on March 27, 2001, at 9:07:54
Hi, Bill. This recent post of mine, below, might help. Be sure to discuss any changes with your pscyhiatrist, who, hopefully, is also a good pharmacologist (very knowledgable about prescribing drugs, their effectiveness outside of official indicated usage, augmentation therapy, combination therapy, etc.) Hopefully, the table referred to in the post will give you a basis for discuss things with your pscyhiatrist. Also, remember that the table, for the most part, is a generalization. Not everyone will have the same experience. And, there are augmentation strategies (i.e, trying a different class of drug in addition to the one you're using) that might work, such as Deprenyl, if your doc doesn't view the combination as dangerous. Further, combination strategies (trying a drug of the same general class in addition to the one you're using) might be effective, such as Wellbutrin, if, again, your psychiatrist feels the combination isn't too dangerous.
Lastly, you could, of course, trying waiting things out and seeing if they get better. As bad as your issue may seem to you, it is much better than the complete anorgasmia I have experienced with Nardil. I'd trade places any time.
See you.
JB
Posted by jb on March 28, 2001, at 10:11:32I discovered a very informative article which includes a table indicating the side effects of many Antidepressants, including, in many cases, the pharmacological reasons for the side effect. With the exception of MAOI's, the table seems to be relatively complete. The article can be found at http://pharmacy.orst.edu/dur/news/2_3/2_3.htm
Hope this helps.By the way, a few observations I was able to make from the table in the article:
(1) Sexual dysfunction side effect - attributable to all SSRI's and any other AD, such as Nardil, which inhibit the reuptake of serotonin.(2) No sexual dysfunction side effect - attributable to drugs which either block 5HT2a post-synapse (that is, do not allow the serotonin messenger to pass it's message along), e.g., Serzone. Also for drugs which exhibit little or no 5HT2 effect, such as Bupropion, venlafaxine, Mirtazapine, and Reboxetin
(3) Weight gain side effect - any drug which acts upon 5HT2c, thereby stimulating appetite. These drugs include Mirtazapine and, I suspect, Nardil, as well.
JB
This is the end of the thread.
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