![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 12 to 36 of 61. Go back in thread:
Posted by elise on April 15, 2000, at 17:05:45
In reply to Re: Prozac...Elise, posted by JohnL on April 15, 2000, at 3:45:49
>
> > john,
> > thanks for your answer to my questions! I have been on prozac for probably 6 years....and never realized how much i really was affected negatively until you mentioned your problems with it! I thought it was just me. I never really thought that maybe the anxiety i felt was compounded by the prozac ---that's why i was put on neurontin! I think i will decrease my prozac to 20 mg. tomorrow and go to 100 mg. modafinal also and give it a few days. Will let you guys know how it goes. thanks again. elise
>
> Elise,
> It's strange how the negative effects of Prozac were so subtle that I didn't realize it was the Prozac. One day I figured oh what the heck, and did 80mg Prozac. There is a strategy with Prozac where large doses can be taken every few days instead of smaller doses daily. So I thought I would play with it. A few hours after dosing the 80mg, I became agitated, withdrawn, numb, and even more depressed. I spent the rest of the day curled up on a couch totally withdrawn. It was only then that I recognized the anxiety created by Prozac. I had read in literature about the common side effects of anxiety with Prozac, but I figured I must be immune because it didn't seem to have any side effects at all...other than lousy sleep quality. But after that 80mg, I came to know the negative side effects, and realized I had them all along...just more subtle at lower doses. I thought it was just me. But it wasn't. It was the drug.
>
> Since then I have experimented more, and discovered that 5mg is helpful...better than none at all. At 10mg I think I'm on the borderline where that anxiety stuff starts to kick in. So for me, 5mg to 10mg a day is about the limit. More is not always better.
>
> Anyway, like I mentioned earlier, stopping or lowering Prozac abruptly is no problem, if you want to try experimenting with doses. You might find 20mg every other day, or once every three days, is better than any dose taken on a daily basis. Even if you skip a day or two, it's still in your system doing its job. It takes 9 days to be half gone. But of course, the possibility always exists that you may need a higher dose taken daily. In that case, another med to reduce the anxiety side effects would be warranted. My favorite for such a remedy is 2.5mg to 5mg Zyprexa. Not the benzos or anticonvulsants. But as we discussed earlier, one thing at a time...so we know what each modification's results are. Don't want to confuse things too much. I'm wishing you the best. JohnLHey John ---
I took 100 mg. provigil and 30 mg prozac today and guess what? I fell asleep!!! Of course I didn't have the anxiety i had yesterday on 200 mg. , but I certainly did not feel motivated to much of anything. So, I guess I need More than 100 provigil, and I defin tly will cut back my prozac to 20 mg. ,,but in the meantime, since the half life of prozac is so long, how would you dose it for the next few days? Would you skip a day of prozac and increase provigil tomorrow, - I guess my ? is, how would you ramp up on the provigil and decrease prozac??? Thanks again. elise
Posted by JohnL on April 16, 2000, at 1:08:03
In reply to Re: Info on my new wonderdrug....(to JohnL), posted by Ant-Rock on April 15, 2000, at 15:06:10
> Hi John, First of all, way to go with finding your new med. I'm sure you've waited a long time to feel this well and you deserve this breakthrough. I'm truly happy for you. I've always enjoyed reading your posts and have learned a lot from you and the many others here.
> I do have a question,
> would combining adrafanil & Ritalin be a bad idea. I only take 10mg/day ritalin and it hasn't hepled me with my biggest problem which is anhedonia. I feel much the same way you described, and reading about your success has peaked my interest in this med. I see my p-doc this week and had planned on asking to increase the ritalin, but now maybe adding adrafanil instead of increasing would be a better idea. Any suggestions?
>
> AnthonyAnthony,
It would sure be nice if we could ask your question of a qualified physician, but of course Adrafinil is hardly known outside of Europe. My best judgement is that Ritalin and Adrafinil could be combined. Of course it would be highly experimental. But then, a lot of what is done in psychiatry is. A lot of what we know about established popular drugs was derived from experimentation and accidental discovery. For example, Zyprexa as a mood stabilizer and/or an antidepressant, not just an antipsychotic.Ritalin and Adrafinil work in different ways. They work in such a way that there would be no duplication of mechanisms or opposition of mechanisms. I see no reason it couldn't be tried. Adrafinil though requires time. Unlike Ritalin--which, as you know, kicks in quickly--Adrafinil takes days to months to fully work. Three weeks is a minimum. I still have some Ritalin leftover and was pondering the same thing. I'm certainly doing better than in years, but admittedly I'm not quite 100%. So continued tweeking and experimentation is not unlikely. Ritalin+Adrafinil sounds fine to me. That's my best guess. JohnL
Posted by Scott L. Schofield on April 16, 2000, at 1:25:20
In reply to Re: Adrafinil + Ritalin...Anthony, posted by JohnL on April 16, 2000, at 1:08:03
> Adrafinil takes days to months to fully work. Three weeks is a minimum. I still have some Ritalin leftover and was pondering the same thing. I'm certainly doing better than in years, but admittedly I'm not quite 100%. So continued tweeking and experimentation is not unlikely.
I know how hard it is to go even one more hour feeling less than 100% when you think there is something in your magic bag of tricks that might make you feel even better. Patience can be a difficult task to suffer. Please be careful.
- Scott
Posted by allisonm on April 16, 2000, at 20:21:08
In reply to Re: Adrafinil + Ritalin...Anthony...JohnL, posted by Scott L. Schofield on April 16, 2000, at 1:25:20
JohnL,
Weren't you taking Remeron at one time? Are you still?
Posted by allisonm on April 16, 2000, at 20:30:18
In reply to Question for JohnL, posted by allisonm on April 16, 2000, at 20:21:08
JohnL,
Sorry, I didn't see your previous thread. 7.5mg.
Tnx.
Posted by Leighwit on April 17, 2000, at 10:45:26
In reply to RE: DC, posted by AndrewB on April 17, 2000, at 7:47:39
Andrew:
I have a couple of questions for you, please:
You might remember that I tried Reboxetine thru my Pdoc here in the US, and it didn't work for me. That, however, doesn't mean that Adrafinil won't. I'm now taking Wellbutrin with Aricept and Celexa. It's working rather well, (the Aricept is working very well to counteract the memory and concentration side effects) but the Celexa is something I might want to replace at some point. It's still bothering my stomach after four weeks, and I'm concerned about weight gain.
Do you know if Adrafinil can be mixed with Wellbutrin?
Second question: what is anhedonia?
Thanks, Andrew.
Laurie (Leighwit)
Posted by AndrewB on April 17, 2000, at 12:20:23
In reply to Re: RE: DC, posted by Leighwit on April 17, 2000, at 10:45:26
Laurie,
Anhedonia; inability to experience pleasure. For example, you could barely stay awake through the fireworks display and you can't remember what you ate at the gourmet restaurant the night before.
Wellbutrin and adrafinil. I can only guess. It sounds like it would be too stimulating. I believe the mechanics of wellbutrin's action are poorly understood, but to me it seems like wellbutrin mainly enhances norandregenic transmission, as does adrafinil.
AndrewB
Posted by Leighwit on April 17, 2000, at 13:21:34
In reply to Re: Laurie, posted by AndrewB on April 17, 2000, at 12:20:23
Thanks, Andrew. I hadn't heard the word before, but I suffer from anhedonia as a significant aspect of depression. Wellbutrin is the only drug I've taken which treats that particular symptom to some extent. Perhaps, however, I'm confusing productivity with an ability to experience pleasure. I can function when I take Wellbutrin. I do things. But I don't think pleasure is really something I experience any more. Hadn't really thought about it.
The Celexa that I take at night as of a few weeks ago merely takes the edge off the Wellbutrin (i.e, I feel less agitated.) It doesn't elevate my mood, nor do any of the other SSRIs.
On the other hand, I guess I'm feeling some pleasure in that I have some energy and can think clearly, which is a huge relief, for which I am grateful.
Listening to the discussions about Adrafinil and Provigil bringing about some euphoria makes me want for more.
It's a thin line to cross: feeling "functional" and wanting the security that comes from that — or taking a jump in the hopes of feeling even better.
A dilemma that affects us all nearly every day I suppose....
Laurie (Leighwit)
Posted by Andrewb on April 17, 2000, at 14:08:23
In reply to Re: Laurie, posted by Leighwit on April 17, 2000, at 13:21:34
Laurie,
I'm kind of like you. Serzone (an SSRI) and wellbutrin never helped my mood. Wellbutrin made me more alert. Serzone took the edge off things. Some people, sometimes have to look farther afield for an AD that works. I warn you though, if you are going to try unconventional ADs, make sure you use sound judgement. Don't try something on the experience of one person, me or anyone else. Do your research, find out all you can about the prospective med. I suggest that for most people this means gathering up all the printed material you can find on the med., including posts off this board, and presenting the info. to your psychiatrist for review.
AndrewB
Posted by Leighwit on April 17, 2000, at 14:29:43
In reply to Re: Laurie, posted by Andrewb on April 17, 2000, at 14:08:23
Absolutely sound advice, Andrew. I am fortunate that I have a Pdoc who is willing to think "outside of the box" yet thoroughly researches any suggestions I might bring to her. She consulted with a psychopharmacologist at a teaching hospital here in the Chicago area before agreeing to help me acquire and try Reboxetine. She went to quite a bit of trouble actually. I wish it had been the panacea I'd hoped for. I think I'll stick with my WB/Aricept/Celexa cocktail for awhile. If I experience any worsening of symptoms, though, I think I'll talk to her about Adrafinil.
Without this and another ng I read frequently, I wouldn't have known that drugs such as Reboxetine, or Adrafinil even existed. In fact, I learned about Aricept from reading newsgroups, which is now an important part of my treatment. It puts different medications and topics on my list for further research and potential discussion with my Pdoc. By no means, though, would I try new drugs without back-up research and professional expertise.
Great advice, Andrew.
Laurie
Posted by DC on April 17, 2000, at 18:23:42
In reply to RE: DC, posted by AndrewB on April 17, 2000, at 7:47:39
Andrew,
Wow, thanks for all the great information. I'm glad the reboxetine and amisulpride are helping you. I was very interested to read your hyphothesis about subnormal function of D2 receptor. I also think it has something to do with dopamine. The MAOI's all affect dopamine;and lots of time they work better than the ssris. But I also think social anxiety has something to do with gaba receptors. Klonipan is often helpful and so it neurontin. 100mg three times a day might be a good starting dose, but you might need to get up to 300-400mg 3-4/day. The company that makes neurontin is now testing a new drug called pregabalin for anxiety and bipolar disorder. Basically, it's a slightly modified version of neurontin. Right now they conducting a study at Yale Anxiety Disorders Clinic, trying Pregabalin for social phobia. I was going to do it, but decided not because of the restriction on all other meds. I wonder if this drug might work even better for me than neurontin. I'll call the clinic and ask the guy if it seems to be helping people. (But he is so uptight he will probably refuse to say anything).
Good luck, DC
Posted by Fred Potter on April 18, 2000, at 17:03:20
In reply to Re: Laurie, posted by Leighwit on April 17, 2000, at 13:21:34
I find anhedonia a deeply upsetting part of depression. Things you were passionate about are meaningless, and yet you know there's someone inside you who is still passionate about them but can't connect.
As for euphoria, I reckon we all deserve some of that
Fred
Posted by michael on April 18, 2000, at 19:23:22
In reply to Info on my new wonderdrug....Adrafinil., posted by JohnL on April 14, 2000, at 4:26:06
> I can't seem to access my previous post on Adrafinil and Amisulpride. To make a long story short, Adrafinil has been wonderful at treating my longstanding stubborn anhedonia. Finally something that works! Yes!!
>
> It's hard to find much information on Adrafinil. But the stuff I did find--posted below--I can say from personal experience is completely true. Everything this literature says about Adrafinil is absolutely true and accurate. The drug is everything the literature says it is. What a wonderful medication! Adrafinil...SALUTE!!!
>
>
> ADRAFINIL: What is; (a.k.a. Olmifon) (Description & information below)
> NOTE:not to be confused with "Anafranil (a.k.a. clomipramine)" the Antidepressant.
>
> Adrafinil provides alertness in most without the feeling often felt with stimulants that usually are prescribed for a person with
> narcolepsy. Such as amphetamines etc. Also the possibility of tolerance is low with its continued use. There is however a
> need for certain Liver function tests
> on a regular basis with its continued use. Normally the same types of required testing as with the medication " cylert " which is
> commonly prescribed in the USA. It is also used in certain parts europe as a "antidepressant". It is the combination of
> Adrafinil's releasing stimulantive arousal effect(s), and its antidepressant effects that some doctors in europe recommend
> Adrafinil over its newer form of Modafinil. There have been studies done in the United States "measuring depression in
> individuals with sleep disorders",. In one study it was suggested that the
> "rate of narcolepsy and depression is estimated to be between 30-52%".
>
>
> ADRAFINIL (Olmifon)
>
> Rapidly restores vigilance and alertness in older people and the physically and mentally tired. Has a powerful
> antidepressant action far superior to that of fluoxetine (Prozac) and clomipramine (Anafranil) and is without any serious
> side effects. Adrafinil restores your powers of concentration, memory and intellectual function. When administered to
> older people who have lost interest in life, adrafinil makes them want to take part in life again and they find that they
> have renewed energy and vigor. Adrafinil may be correctly described as an anti-aging drug because it directly combats
> degeneration in the part of the brain that allows you to take pleasure in life. Elderly people very often have disturbed
> sleep patterns and take many naps during the day. Adrafinil restores a youthful sleep/wake cycle of full alertness in the
> daytime and deep restorative sleep at night. After several weeks of treatment with Adrafinil daytime sleepiness
> disappears, interest in intellectual activity is restored and depression lifts. It is very important to note that this improved
> quality of alertness is NOT accompanied with mental excitation and insomnia as occurs with amphetamine or caffeine.
> The correct dosage is 300 to 600 mg per day. The dosage can be adjusted according to response. Remember it takes
> three weeks for all the effects of Adrafinil to become apparent. Do not use Adrafinil if you have any type of kidney or liver
> problem or if you suffer from epilepsy.
>
> Where all other drugs have failed, Adrafinil has quickly become the star my show. I can't say enough good about it. JohnLHey John,
Just a couple questions - you mention 300mg - 600mg for dosage, while the package insert thta I got says 600 - 1200. I was just curious of the source for the dosage that you mentioned?
I was also wondering how long it was before you "noticed" anything that you would attribute to the adrafinil? Couple of days, couple of weeks? And if you could label it, would you call it energy? "hedonia"? Ability to concentrate/focus?
And one last dosage question - did you mention that it did affect your sleep for the first few days? And if that's correct, is it fair to say that you haven't had any issues with that subsequently, as long as you don't take any after early afternoon?
Thanks for any info you can provide, and sorry if I'm re-asking question you've already addressed.
michael
Posted by DC on April 18, 2000, at 17:07:59
In reply to Re: Laurie, posted by Leighwit on April 17, 2000, at 13:21:34
Reading over the posts here, I am getting enthusiastic about these three new drugs.
1. Is provigal the same thing as modafinal, and why is it only being used for narcrolepsy? If it has AD effects?2. Are these three drugs all in the same class? Are they all stimulant type drugs?
3. Which one do you think would be most likely to help someone with a combination of anhedonia, inattentive add, and social phobia?
I'm sorry I can only ask questions at this point. Any help would be greatly appreciated. Thanks, Dwight
Posted by JohnL on April 19, 2000, at 2:53:07
In reply to JohnL. Re: Q's on new wonderdrug....Adrafinil., posted by michael on April 18, 2000, at 19:23:22
Michael,
The information I provided--such as the dosing range of 300mg t0 600mg--was copied from a net search. It wasn't my own writing. You are correct that the package label specifies doses of 600mg to 1200mg, but apparently less may work fine.
I noticed immediate effects of Adrafinil in terms of great mood and energy. But that faded in two days. It returned gradually over a period of two weeks in a slow but steady improvement. My mood actually is not as good as it was the first day (three weeks later). But interest, concentration, and motivation are strong. I don't physically feel any more energy than normal, but mentally I just want to do things. Previously, all I could do was keep the couch occupied.
It did indeed affect sleep during the first week. It was terrible. I could fall asleep OK, but then wake just a couple hours later. Midnight insomnia. Not even my Remeron was strong enough to overcome it. That did however disappear completely after a week. I sleep fine now.
JohnL
Posted by michael on April 19, 2000, at 3:11:18
In reply to Re: Adrafinil....Michael, posted by JohnL on April 19, 2000, at 2:53:07
> Michael,
>
> The information I provided--such as the dosing range of 300mg t0 600mg--was copied from a net search. It wasn't my own writing. You are correct that the package label specifies doses of 600mg to 1200mg, but apparently less may work fine.
>
> I noticed immediate effects of Adrafinil in terms of great mood and energy. But that faded in two days. It returned gradually over a period of two weeks in a slow but steady improvement. My mood actually is not as good as it was the first day (three weeks later). But interest, concentration, and motivation are strong. I don't physically feel any more energy than normal, but mentally I just want to do things. Previously, all I could do was keep the couch occupied.
>
> It did indeed affect sleep during the first week. It was terrible. I could fall asleep OK, but then wake just a couple hours later. Midnight insomnia. Not even my Remeron was strong enough to overcome it. That did however disappear completely after a week. I sleep fine now.
> JohnLHey JohnL,
Thanks for the reply. I had a couple of other things I wanted to ask you come to mind... One was about Ultram (tramadol). I believe it's a pain med (works w/opoid receptors? not sure about that...), but I've seen it mentioned here a couple times in conjunction with alieviating anhedonia. Not that it was prescribed for that, just that people noticed that it seems to help. Just wondering if you've had any experience w/that one - since you mentioned anhedonina as an aspect that's been hard to address?
The other thing was selegiline. If I recall correctly, you had been experimenting w/that as well? Low dosage - 5mg to 15mg? Just wondering if you've left that one behind, or still keeping it in your arsenal, even if not employing it just now. I thought you'd had some positive results...? Think the metabolites might be a bit much in conjunction w/the adrafinil - in terms of stimulation & difficulty sleeping?
Thanks again for all of you time JohnL, responding to me, as well as all the great info you provide in general. michael
Oh, one more thing - as for the adrafinil, have you been going w/300mg am & noon, for dosages & dose timing? Thanks again.
Posted by JohnL on April 19, 2000, at 3:13:06
In reply to Provigil, Adrafinal, and Amisulpride, posted by DC on April 18, 2000, at 17:07:59
> Reading over the posts here, I am getting enthusiastic about these three new drugs.
> 1. Is provigal the same thing as modafinal, and why is it only being used for narcrolepsy? If it has AD effects?
>
> 2. Are these three drugs all in the same class? Are they all stimulant type drugs?
>
> 3. Which one do you think would be most likely to help someone with a combination of anhedonia, inattentive add, and social phobia?
>
> I'm sorry I can only ask questions at this point. Any help would be greatly appreciated. Thanks, Dwight
Yes, Provagil is Modafinil. Though its designated use is in narcolepsy, it has shown promise in other conditions as well. I think all drugs do actually. For example, Zyprexa for depression or mood stability, not just schizophrenia. Lamictal for depression and mood stability, not just epilepsy. Prozac for OCD, not just depression. On and on. Etc.Modafinil and Adrafinil are technically psychostimulants, though their profiles are quite different (more subtle, smoother, takes longer) than typical stimulants. Amisulpride is a European antipsycotic technically. But it is somewhat alerting, not often sedating.
For your symptoms, I personally feel any one of these could work better for you than the SSRIs or other standard antidepressants. That's my personal experience anyway. SSRIs and stuff seem pretty effective at relieving depression, but they often don't affect a few core symptoms. Anhedonia seems to be a most stubborn condition, which I think responds better to NE drugs like Adrafinil or Modafinil (or tricyclics), and dopamine drugs like Amisulpride.
I think Adrafinil is worth trying first, because it is easy to get without a prescription, and it's fairly cheap. Modafinil can also be found without a prescription from overseas, but it is very pricey...more so than what you are used to paying for any other psychiatric drugs. Amisulpride requires a prescription, regardless of where you get it, 50 tabs of 200mg are a little over $200. But at 50mg to 100mg a day normal dosage, those 50 tabs will last 100 to 200 days. So the expense isn't too bad, but actually getting it is not as easy as Adrafinil.
I've tried Amisulpride alone, Adrafinil alone, and the two combined. Amisulpride provided amazing social comfort, relaxation, and confidence. But it did little for anhedonia. Adfrafinil is great for both social phobia and ADD and depression, all in one. So again, I tend to lean toward Adrafinil as your first, easiest, and cheapest choice. I am taking both Adrafinil and Amisulpride. Though I'm not 100%, I'm way better than on any of the dozens of antidepressants and things I've tried over the years.
JohnL
Posted by michael on April 19, 2000, at 3:47:53
In reply to Re: Provigil, Adrafinal, and Amisulpride, posted by JohnL on April 19, 2000, at 3:13:06
Hey JohnL-I tried it, and I was out like the proverbial light bulb - slept 12+ hours/day.
However, it just recently occured to me that I still had prozac in my system (had been taking 20mg/day) while I was trying the amisulpride - I had almost no wash-out period between the meds. Think it might affect me differently now, w/o the prozac in my system? I'm planning to give adrafinil a shot, begining tomorrow... anyway, thanks again... michael
> > Reading over the posts here, I am getting enthusiastic about these three new drugs.
> > 1. Is provigal the same thing as modafinal, and why is it only being used for narcrolepsy? If it has AD effects?
> >
> > 2. Are these three drugs all in the same class? Are they all stimulant type drugs?
> >
> > 3. Which one do you think would be most likely to help someone with a combination of anhedonia, inattentive add, and social phobia?
> >
> > I'm sorry I can only ask questions at this point. Any help would be greatly appreciated. Thanks, Dwight
>
>
> Yes, Provagil is Modafinil. Though its designated use is in narcolepsy, it has shown promise in other conditions as well. I think all drugs do actually. For example, Zyprexa for depression or mood stability, not just schizophrenia. Lamictal for depression and mood stability, not just epilepsy. Prozac for OCD, not just depression. On and on. Etc.
>
> Modafinil and Adrafinil are technically psychostimulants, though their profiles are quite different (more subtle, smoother, takes longer) than typical stimulants. Amisulpride is a European antipsycotic technically. But it is somewhat alerting, not often sedating.
>
> For your symptoms, I personally feel any one of these could work better for you than the SSRIs or other standard antidepressants. That's my personal experience anyway. SSRIs and stuff seem pretty effective at relieving depression, but they often don't affect a few core symptoms. Anhedonia seems to be a most stubborn condition, which I think responds better to NE drugs like Adrafinil or Modafinil (or tricyclics), and dopamine drugs like Amisulpride.
>
> I think Adrafinil is worth trying first, because it is easy to get without a prescription, and it's fairly cheap. Modafinil can also be found without a prescription from overseas, but it is very pricey...more so than what you are used to paying for any other psychiatric drugs. Amisulpride requires a prescription, regardless of where you get it, 50 tabs of 200mg are a little over $200. But at 50mg to 100mg a day normal dosage, those 50 tabs will last 100 to 200 days. So the expense isn't too bad, but actually getting it is not as easy as Adrafinil.
>
> I've tried Amisulpride alone, Adrafinil alone, and the two combined. Amisulpride provided amazing social comfort, relaxation, and confidence. But it did little for anhedonia. Adfrafinil is great for both social phobia and ADD and depression, all in one. So again, I tend to lean toward Adrafinil as your first, easiest, and cheapest choice. I am taking both Adrafinil and Amisulpride. Though I'm not 100%, I'm way better than on any of the dozens of antidepressants and things I've tried over the years.
> JohnL
Posted by CarolAnn on April 19, 2000, at 9:55:21
In reply to Re: Provigil, Adrafinal, and Amisulpride, posted by JohnL on April 19, 2000, at 3:13:06
I keep reading in this thread that Adrafinal is easy to get without a prescription, but I haven't seen anything(or maybe I missed it) about whether you can get it *with* a prescription from your Pdoc. The way my insurance works I would only have to pay $8.00 per month's supply. Also, is that cheaper then just ordering the stuff on my own? Thanks, in advance, for the info! CarolAnn
Posted by michael on April 19, 2000, at 10:31:21
In reply to Re: Adrafinal Query (hope it's not redundant), posted by CarolAnn on April 19, 2000, at 9:55:21
> I keep reading in this thread that Adrafinal is easy to get without a prescription, but I haven't seen anything(or maybe I missed it) about whether you can get it *with* a prescription from your Pdoc. The way my insurance works I would only have to pay $8.00 per month's supply. Also, is that cheaper then just ordering the stuff on my own? Thanks, in advance, for the info! CarolAnn
CarolAnn-
Adrafinil isn't approved by the FDA, and therefore isn't available in the US. You can order it from abroad.
Btw - the dosage seems to be 300mg to 1200mg per day (or 1 to 4 pills per day), so if you can get your insurance to subsidize you, $8 per month is definitely cheaper.
If you can get a script, you may be able to get it cheaper via a french pharmacy - I once saw someone else mention that it was roughly $12 for a box of 40x300mg, or $40 for 160x300mg in france.
But don't know how your insurance co. would deal with/feel about covering a med not approved by the FDA...?
Good luck! & let us know how that works if you persue this w/your ins. co. - I'd be curious about their reaction. michael
Posted by AndrewB on April 19, 2000, at 13:22:44
In reply to Provigil, Adrafinal, and Amisulpride, posted by DC on April 18, 2000, at 17:07:59
Dwight,
You don't have to try just one. I take reboxetine and amisulpride and they both help. Amisulpride makes me less socially anxious and it also works as a prohedonic. Reboxetine works to get me out and do things such as sociallize. Adrifinil seems to do the same thing. One good reason to do a trial with amisulpride is that it is easy. The trial will only take 5 days to a week to decide whether amisulpride will work for you, it acts that fast. And since you are a man, you shouldn't expect to have to experience much in the way of side effects during your trial.
Dwight, what is inattentive ADD?
AndrewB
Posted by Ant-Rock on April 19, 2000, at 17:49:01
In reply to Re: Provigil, Adrafinal, and Amisulpride, posted by AndrewB on April 19, 2000, at 13:22:44
Hi again Andrew,
Hope all is well. How is the rebox-amisulp combo working? Sounds like your doing well, hope that is the case. JohnL's posts sure were exciting to read. I love to hear about ones life being turned around do to their will to live and perseverence.
Anyway, thanks in advance,
Anthony
Posted by Janice on April 19, 2000, at 22:38:17
In reply to Re: Provigil, Adrafinal, and Amisulpride, posted by AndrewB on April 19, 2000, at 13:22:44
Hi Andrew,
From what I understand, there are a group of people with ADD who have never been hyper (mostly women) but still have ADD. Instead of being hyper, they have always been hypo. It looks very much like depression and often is accompanied with a low grade chronic depression.
One good way to tell it apart from depression is that the symptoms go back into childhood--maybe not the depression symptoms.
I don't know why there is so little decent information about it. I would never have known it existed by reading any ADD sites. I think it is a new diagnosis within the past 5 years. These are probably the people who think they are depressed, and have been depressed for SO long, they finally in desperation try a stimulant…which WORKS. The medical profession, up until recently, thought some people's 'depression' could only be treated with stimulants.
Take care Andrew, Janice
Posted by Paul S. on April 20, 2000, at 1:56:24
In reply to Info on my new wonderdrug....Adrafinil., posted by JohnL on April 14, 2000, at 4:26:06
I am interested in trying Adrafanil but am going to run it by my doctor first. It is not available in Canada and was wondering if anyone knew if there are any concerns/problems I should be aware of in ordering from out-of-country into Canada.
Thanks!
PaulS
Posted by AndrewB on April 20, 2000, at 7:41:08
In reply to Re: Provigil, Adraf...to:AndrewB, posted by Ant-Rock on April 19, 2000, at 17:49:01
Hey Anthony!
I'm trying to keep track of people's different responses to amisulpride. Could you please sum up for me what it has or hasn't done for you. Have you found anything to improve your energy.
I'm doing fine myself. I added amineptine onto the other meds with good results so far. It is good for energy, drive, and confidence.
AndrewB
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