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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by michele b on March 27, 2000, at 0:08:15
i know we are all different but i would be pleased to hear different peoples experiences with gainingweight whilst on ads. best wishes to all struggling with the black dog.
michele b.
Posted by JohnL on March 27, 2000, at 4:34:58
In reply to what is the ssri least likely to cause weight gain, posted by michele b on March 27, 2000, at 0:08:15
> i know we are all different but i would be pleased to hear different peoples experiences with gainingweight whilst on ads. best wishes to all struggling with the black dog.
> michele b.As you said, we're all different. But speaking in broad generalities, Prozac is probably the least likely in the SSRI class to cause weight gain. A listed possible side effect is weight loss. I would rate Zoloft as the second least likely to cause weight gain. But again, broad generalities. Some people actually gain weight instead. But the odds are more in your favor with in Prozac.
Posted by Phil on March 27, 2000, at 7:20:17
In reply to what is the ssri least likely to cause weight gain, posted by michele b on March 27, 2000, at 0:08:15
John's right. But for me personally, and I've taken A LOT of AD's, they have all caused weight gain. Not true for everyone but I would wager a very high percentage of people, on any AD gain weight.
Posted by kate on March 27, 2000, at 10:49:44
In reply to Re: what is the ssri least likely to cause weight gain, posted by Mick on March 27, 2000, at 10:29:35
wellbutrin made me lose a ton of weight and actually used to be used as an appetite suppresant a long time ago. i have talked to a LOT of people who have had the same experiences on the drug. if you already thin, watch out for this drug, it can be dangerous for those who are at a good weight or are already underweight.
~kate
Posted by Renee N on March 27, 2000, at 21:58:41
In reply to Re: what is the ssri least likely to cause weight gain, posted by Mick on March 27, 2000, at 10:29:35
> Since I've been on Effexor XR I have lost almost ten pounds. I am also taking an AD stimulant, Pemoline, biking every other day and severely limiting animal fats. Unfortunately you really have to work at it every day.
Please tell me more about Pemoline. I take Effexor XR and ADDerall for ADHD and anxiety and depression. ADHD is my worst problem. I lost weight, by changing to low animal fat diet and walking, pushups, and crunches, before I took any meds. I lost more on Wellbutrin, but have gained almost 10 back since taking Effexor.
Give yourself a giant pat on the back from me for your healthy efforts at physical and mental fitness! Consider it one more exercise for today!8^) Renee N
Posted by Mick on March 28, 2000, at 8:27:26
In reply to Pemoline?, posted by Renee N on March 27, 2000, at 21:58:41
> Please tell me more about Pemoline.I was diagnosed with attention deficit in 1996. My doctor prescribed Ritalin but wasn't on it more than two weeks as I could not handle the wired feeling on the drug. Last November my psychiatist prescribed Cylert 37.5 mg. [Pemoline is generic] as a stimulant with Paxil for depression after I quit alcohol. The first week I had some trouble sleeping but later I noticed no side affects. Now I do have less distractions, more concentration and more energy to accomplish my daily agenda. Switching from Paxil to Effexor XR helped the depression and I feel much better. Attached is info gathered from several web sites:
Pemoline ( Cylert )Pemoline ( Cylert ) is used to treat attention-deficit-disorder in children. This drug is from a
family of drugs known as central nervous system stimulants. Originally used in older persons to
improve cognitive functioning.Do not give this drug to child that suffer from psychotic disorders that produce the symptoms of
attention-deficit-disorder.Long term use may affect growth.
Warnings
Do not take monoamine oxidase inhibitor with this drug.
Do not take this drug with heterocyclic antidepressants.
The habit-forming potential is high. Psychological and physical dependence is possible. Addiction is rare
in children but a problem with adults.Children who take this drug on a long-term basis should be examined every four to six months. The
physician should monitor height and weight, look for the presence of tics, measure blood pressure and
pulse, and ask about side effects. ( Yudofsky, Hales & Ferguson )Do not take this drug if you are pregnant or if planing to become pregnant. Do not take if you are
breast-feeding.Do not give this drug to children under the age of six and if over sixty with close monitoring.
Do not use if: You had negative reactions to this drug in the pass.
Inform your Doctor if: You had negative reactions to this drug in the pass. If you have
epilepsy / family history of seizures, a history of Touette's syndrome, liver / kidney / heart disease. If
you are taking any other prescription or non-prescription drug. If you plan to be under anesthesia or
having any surgery in the next few months, also if you will be under-going any medical tests. If you
have taken a monoamine oxidase inhibitor ( MAO ) in the pass two weeks.Pemoline ( Symptoms or Effects )
Common: Nausea, loss of appetite, difficulty sleeping or weight loss.
Rare: Abdominal pain, headache, drowsiness, dizziness, mood changes, lack of coordination,
tics/unusual movements, skin rash, yellow eyes / skin or chest pain.See physician always: Abdominal pain, drowsiness, dizziness, mood changes, lack of coordination,
tics/unusual movements, skin rash, yellow eyes / skin , chest pain, difficulty sleeping or weight loss.See physician if severe: Nausea, loss of appetite or headache.
Stop taking and see physician NOW: Abdominal pain, tics/unusual movements, chest pain, skin
rash or yellow eyes / skin.Cylert,pemoline,cylert,Pemoline,add,adhd,treatment,side effects
Cylert,pemoline,cylert,Pemoline,add,adhd,treatment,side effects
Cylert.
Side Effectsfrom the "PHYSICIAN'S DESK REFERENCE®"*:
"CYLERT® Tablets [ci'lert] (Pemoline)
CLINICAL PHARMACOLOGY
CYLERT (pemoline) has a pharmacological activity similar to that of other known central nervous system
stimulants; however, it has minimal sympathomimetic effects. Although studies indicate that pemoline (CYLERT)
may act in animals through dopaminergic mechanisims, the exact mechanism and site of action of the drug in man is
not known.There is neither specific evidence which clearly establishes the mechanism whereby CYLERT produces its mental
and behavorial effects in children, nor conclusive evidence regarding how these effects relate to the condition of the
central nervous system.WARNINGS
Decrements in the predicted growth (i.e., weight gain and/or height) rate have been reported with the long term use
of stimulants in children. Therefore, patients requiring long-term therapy should be carefully monitored.PRECAUTIONS
General: Clinical experience suggests that in psychotic children, administration of CYLERT may exacerbate
symptoms of behavior disturbance and thought disorder.CYLERT should be administered with caution to patients with significantly impaired renal function.
Laboratory Tests: Liver function test should be performed prior to and periodically during therapy with CYLERT.
The drug should be discontinued if abnormalities are revealed and confirmed by follow-up tests. (See "ADVERSE
REACTIONS" section regarding reports of abnormal liver function tests, hepatitis and jaundice.)Pediatric Use: Safety and effectiveness in children below the age of 6 years have not been established.
Long-term effects of CYLERT in children have not been established (See "WARNINGS" section).
CNS stimulants, including pemoline (CYLERT), have been reported to precipitate motor and phonic tics and
Tourette's syndrome. Therefore, clinical evaluation for tics and Tourettte's syndrome in children and their families
should precede use of stimulant medications.Drug treatment is not indicated in all cases of ADD with hyperactivity and should be considered only in light of
complete history and evaluation of the child. The decision to prescribe CYLERT (pemoline) should depend on the
physician's assessment of the chronicity and severity of the child's symptoms and their appropriateness for his/her
age. Prescription should not depend solely on the presence of one or more the behavioral characteristics.ADVERSE REACTIONS
The following are adverse reactions in decreasing order of severity within each catagory associated with CYLERT:Hepatic: There have been reports of hepatic dysfunction including elevated liver enzymes, hepatitis and jaundice in
patients taking CYLERT.Hematopoietic: There have been isolated reports of aplastic anemia.
Miscellaneous: Supression of growth has been reported with the long-term use of stimulants in children. (See
"WARNINGS" section.) Skin rash has been reported with CYLERT.Central Nervous System: The following CNS effects have been reported with the use of CYLERT: convulsive
seizures; literature reports indicate that CYLERT may precipitate attacks of Gilles de la Tourette syndrome;
hallucinations; dyskinetic movements of the tongue, lips, face and extremeities; abnormal oculomotor function
including nystagmus and oculogyric crisis; mild depression; dizziness; increased irritability; headache; and
drowsiness.Insomnia is the most frequently reported side effect of CYLERT; it usually occurs early in therapy prior to an
optimum therapeutic response. In the majority of cases it is transient in nature or responds to a reduction in dosage.Gastrointestinal: Anorexia and weight loss may occur during the first weeks of therapy. In the majority of cases it
is transient in nature; weight gain usually resumes within three to six months.Nausea and stomach ache have also been reported.
DRUG ABUSE AND DEPENDENCE
Controlled Substance: CYLERT is subject to control under DEA schedule IV."
an excerpt from "The Essential Guide to Psychiatric Drugs"*:
"STIMULANT ANTIDEPRESSANT DRUGS
Depression may also be treated with drugs called psychostimulants. Use of such drugs is reserved for only two
situations: (1) patients who have failed to respond to at least two other antidepressants and psychotherapy and who
are seriously depressed, and (2) patients with serious and usually terminal medical illnesses such as cancer or AIDS
who are depressed and too sick to take other kinds of antidepressants.The reason for these restrictions is that the stimulant drugs are addictive. They include amphetamines, sometimes
called "speed" or "uppers," methylphenidate (Ritalin), and pemoline (Cylert). The drugs produce a short-term
mood elevation even in people who are not depressed. College students take them to stay awake ail night and finish
term papers.In most people the effects of these stimulant drugs are short-lived and there is often a letdown or "crash" after they
wear off. During this "crash" the patient can feel very depressed, sleepy, and sluggish. Furthermore, and very much
unlike the other drugs discussed so far in this chapter, stimulant drugs have the potential to induce "tolerance."
People who abuse amphetamines and other stimulants--usually in attempts to lose weight or stay awake for
prolonged periods--often find that a dose that had worked for a while is suddenly ineffective and they need a higher
dose. They then become "tolerant" to the higher dose and have to increase the dose again. Soon, the person is
addicted to the drug. Stopping it suddenly leads to a severe withdrawal reaction characterized by bad depression and
extreme fatigue. Suicides have been reported in people who suddenly stop taking amphetamines.Given all these problems, why even mention the stimulant drugs? Simply because they are the only drugs that work
for some depressed patients. A very small group of usually chronically depressed patients seems to be resistant to
every other treatment for depression. These people usually function at a fairly low level relative to their ability and
they feel sad and blue all of the time. They complain of fatigue, low interest in life, and inability to concentrate. Many
say they have been depressed since childhood.Another small group of patients with very serious medical problems also develops depression. Sometimes the
medical problems they have make other antidepressant drugs unsafe, or the medical problems so magnify the side
effects of the other antidepressants that the dying patient is made even more uncomfortable. Stimulant drugs may
actually be the safest choice in this situation.For these two groups of patients stimulant drugs may be the only answer, even though the patient will probably
become addicted. This is not to be taken lightly. The decision to place a patient on a stimulant drug for depression is
serious and must be done only after all other efforts are declared either unsafe or ineffective. The patient must
understand that he will probably become addicted to the medication and that he should never stop taking it abruptly."
an excerpt "The People's Pharmacy" Avon Books, and St. Martin's Press (1976)*:
"Some health professionals fear that these medications may end up being overprescribed. Dr. Carl Kline, an expert
in the field of learning disabilities from the University of British Columbia, has this to say, 'It is my belief that if these
drugs were outlawed, children would not be at all deprived of essential medication, but that doctors would be forced
to make more accurate diagnoses and seek better means of handling the hyperactive behavior of a certain small
percentage of their little patients.'"Do these drugs make a difference in the long-term outcome of the minimal brain
dysfunction? The above referenced book goes on to say..."Until recently, the most important question concerning Ritalin or Amphetamine administration has not been asked.
Do these drugs make a difference in the long-term outcome of the minimal brain dysfunction? A comprehensive
examination of this subject carried out at the Montreal Children's Hospital discovered a startling fact. At the end of
five years, hyperkinetic children who received drugs (either Ritalin or Chloropromazine) did not differ significantly
from children who had not received. Although it appeared that hyperactive kids treated with Ritalin were initially
more manageable, the degree of improvement and emotional adjustment was essentially identical at the end of five
years to that seen in a group of kids who had received no medication at all.Before parents throw their hands up in despair, they might want to consider another approach to the treatment of
hyperkinesis. Dr. Feingold has come up with a revolutionary new treatment for this disorder. Dr. Feingold believes
that diet may have a lot to do with the problem in the first place."*NOTE: Much of the information here presented has been addressed by literally hundreds of individuals seeking the same solutions, to the same answers, with which you are now
engrossed. Such materials have been compiled, reviewed and corrected to the best of the authors ability. It is presented for educational purposes. It is your personal responsibility to
determine the validity of any and all information presented. This compound is NOT a drug and NOT represented as having any medicinal value, it is a nutritional supplement and NOT a
drug. This is not intended to diagnose, treat, cure or prevent any disease. The author hereby delcares that this writing is made without any statement or declaration which would represent
that he/she is a doctor**, licensed medical professional, or other type of medical counselor. **NOTE: IF THERE ARE ANY QUESTIONS THAT COME TO MIND THAT MAY NOT
BE EASILY ANSWERED THROUGH YOUR RESEARCH AND THE HERE INCLUDED CITATIONS, PLEASE CONSULT THE APPROPRIATE MEDICAL
PROFESSIONAL.The materials presented here are done so under the benefit and authority of the First Amendment to the Constitution of the united States of America and said authority
pertains to that Freedom of Speech and Freedom of the Press, ordained and preserved to the benefit of all peoples.
The "PHYSICIAN'S DESK REFERENCE®", and PDR® are registered trademarks owned by Medical Economics. "The Essential Guide to Psychiatric Drugs" is published by St.
Martin's Press.
Posted by Renee N on March 28, 2000, at 15:38:04
In reply to Re: Pemoline?, posted by Mick on March 28, 2000, at 8:27:26
Thanks,you really told me a lot! What does your doctor say about the possibility of liver problems. This is the part that scares me with Cylert. My pdoc has tried me on methylphenidate(Ritalin), dextrostat(Dexedrine), and ADDerall with little improvement. He hasn't suggested trying Cylert. Does your ADHD cause memory problems for you? Does the Cylert help? Have you ever tried ADDerall or Dexadrine?
Posted by Mick on March 29, 2000, at 10:04:20
In reply to Thanks, Mick..., posted by Renee N on March 28, 2000, at 15:38:04
My psych didn't mention liver problems since I assume the dose is so low [37.5 mg. once daily]. I do need to go to my primary care doc for a physical to check liver functions... been waiting until I lose a little more weight. I have adapted to AD memory problems by always writing down things to do in an daily agenda book. This is the way I have learned to cope. Memory is also naturally getting fragmentated after forty/fifty. Cylert does help me keep focused on the things I want/need to do daily and throughout the week. I have never tried ADDerall and my experiences with dex in college were ordeals... great for cramming, etc. but I felt too nervous coming back down. Today I know I wouldn't tolerate it well as Ritalin made me feel that way also. In your case it may be necessary to play with the dosage plus use coping techniques that become second nature. I have also felt generally better by taking more vitamin supplements [B's, C's, Niacin, etc.] which combat depression. Read 7 weeks to Emotional Healing by Dr. Joan Mathews Larson [www.healthrecovery.com/]. Her program specifically targets many emotional problems thru nutrition, chemical imbalances, environmental toxins. It has helped me . Now all I need to do is get back to work since I have been laid-off since October!
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
[email protected]
Script revised: February 4, 2008
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Copyright 2006-17 Robert Hsiung.
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