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Dr. Bob is Robert Hsiung, MD,
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Posted by FaithT on January 24, 2005, at 4:19:29
In reply to Re: STOPPING Effexor made easy - alternatives, posted by not2late4u on January 24, 2005, at 0:43:01
Hello everyone~
I would like to start a NEW thread below, since this one is getting old. I'm concerned that someone in a true state of clinical depression, may decide not to take Effexor based on what they have read under this thread. The original title of THIS thread was "Anyone Had Success On Effexor XR?" I pray that a real tradgedy does not occur, because someone in a weakened state of mind, follows the advice of a poster here, and not a medical professional. Possibly someone may have been looking for some hope, by making that original post.
I kindly ask that the subject line of this new thread be replied to, by POSITIVE experiences, because they ARE out there. I think there are enough negative ones already for people to read if they choose,and I respect that. So, PLEASE respect what I am asking.
Sincerely, Faith~
Posted by Larry Hoover on January 24, 2005, at 5:56:30
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!! » dancingstar, posted by corafree on January 23, 2005, at 13:38:16
> Tks DS...got that...what a giant link!!!
>
> So, seems maybe Allegra preferred over Benadryl in second post.That's not what this article is saying at all.
Some SSRIs inhibit the 3A4 liver enzyme. That can cause an induced (unnatural) toxicity of the listed antihistamines (in the first post on that page).
Diphenydramine (Benadryl), chlorpheniramine (Chlortripilon?) and loratidine (Claritin) do not require the function of 3A4 to be cleared from the system, and are safe to use with antidepressants. Diphenhydramine has anticholinergic activity, which may be why it is especially useful during withdrawals.
Lar
Posted by Larry Hoover on January 24, 2005, at 5:58:11
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!!, posted by eeyorena on January 23, 2005, at 19:50:37
> That's very interesting. My doc has me on Allegra because I take an MAOI now...because I'm not allowed to take Benadryl on an MAOI (related to blood pressure somehow.)
>
> Hmmm.Benadryl is a substrate (is broken down by) MAO, the enzyme monoamine oxidase. If you on an MAO inhibitor, it doesn't break down, and you get overdose-like effects.
Lar
Posted by dancingstar on January 24, 2005, at 10:39:02
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!! » eeyorena, posted by Larry Hoover on January 24, 2005, at 5:58:11
YEP. :-). I didn't understand the full ramifacations or, frankly, the lack there of, but I knew enough to let you guys know when I saw it so that we can try to get some better answers before anyone gets hurt.
Posted by dancingstar on January 24, 2005, at 10:54:15
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!! » eeyorena, posted by Larry Hoover on January 24, 2005, at 5:58:11
Lar,
For purposes of withdrawal, does it appear to be safer if people use either the antihistamine without the SSRI or the SSRI without the antihistamine, or does adding the antihistmine into the mix automatically create a problem, do you think, if they have been previously taking a SSRI or an SNRI...or don't you have a clue or not want to say, also, I'm thinking, a valid answer :-)?
This makes me so mad. When I mentioned that I had been taking Benadryl to get over the E-withdrawl, my poor internist was shocked to hear that it worked, and he hadn't known anything else about it except he was very glad that it helped. He had wanted to give me P, but I wanted no part of the stuff. From what I understand, many if not most are taking a combo of an anithistamine and Prozac at the same time to help them with symptoms, and this could really be a bad idea!~
Bebe
Posted by Larry Hoover on January 24, 2005, at 11:41:08
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!! » Larry Hoover, posted by dancingstar on January 24, 2005, at 10:54:15
> Lar,
>
> For purposes of withdrawal, does it appear to be safer if people use either the antihistamine without the SSRI or the SSRI without the antihistamine, or does adding the antihistmine into the mix automatically create a problem, do you think, if they have been previously taking a SSRI or an SNRI...or don't you have a clue or not want to say, also, I'm thinking, a valid answer :-)?It really depends on which drugs you're considering. See below.
> This makes me so mad. When I mentioned that I had been taking Benadryl to get over the E-withdrawl, my poor internist was shocked to hear that it worked, and he hadn't known anything else about it except he was very glad that it helped. He had wanted to give me P, but I wanted no part of the stuff. From what I understand, many if not most are taking a combo of an anithistamine and Prozac at the same time to help them with symptoms, and this could really be a bad idea!~
>
> BebeYour internist may not have heard of Benadryl as a treatment for withdrawal side-effects because it's very likely been discovered quite by accident.
What I see throughout your post is a shifting back and forth between the general and the specific. There are some combinations of antidepressants and antihistamines that are a problem. Others are safe.
It is not okay to just think "I'll take an antihistamine to counteract the side-effects of withdrawal"....the drug to consider is *one* antihistamine, diphenhydramine (Benadryl). You can't just substitute willy-nilly for Benadryl. Based on the data on the tips page, chlorphenhydramine is a possible alternative to Benadryl. The modern non-sedating antihistamines are not acceptable because they require processing in the liver, and most modern antidepressants inhibit liver function.
Prozac works to help with withdrawal because of its very lengthy half-life. It virtually self-tapers in dose. Prozac and Benadryl together are also safe.
Lar
Posted by corafree on January 24, 2005, at 12:02:19
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE, posted by FaithT on January 24, 2005, at 4:19:29
Yep, Eff-XR is the first AD that has really helped me. I am emotional; sensitive. My prob' = reacting w/ brutal honesty, or separation anxiety.
Anyway, those tendencies have been less on Eff-XR. I take 150mg am and 75mg late afternoon as am a fast metabolizer and use up med very quickly, and haven't much fat on body, so don't store up things well.
My level of anxiety and depression is much better. I wonder sometimes if my dx actually should have been anxiety disorder to begin w/; first became depressed about being so anxious!
Of course, now, 20yrs later, every other AD tried, I am borderline; feel damaged by all those AD trials.
I really have to be aware of regimen; not miss a dose tho', as if do, become anxious, worry, feel inept, and agoraphobic.
In future, would love being drug free again; if opportunity seems plausible (knowing my own limitations); for now am hanging on better than in past. cf
Posted by medhed on January 24, 2005, at 12:20:22
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE, posted by FaithT on January 24, 2005, at 4:19:29
nope, not positive. i didn't need this board to know i felt poisoned. i do know people who swear by it though, i guess as long as you keep taking it you won't have a problem. some people are good candidates for this drug and that was why i tryed it. it was worth trying, that's why i took it for 8mos...people are different, i just wish my doc knew that. ("you can't be having that side effect, it isn't in the insert!") says she.
Posted by FaithT on January 24, 2005, at 12:56:50
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE, posted by FaithT on January 24, 2005, at 4:19:29
Thanks everyone~
If you have something postive to say about Effexor, please post it there. I have nothing to gain by doing this, except to try and give another view of this drug, to others that may need some hope.
Cora, I appreciate your post. Thank you.
Best wishes, Faith~
Posted by dancingstar on January 24, 2005, at 13:33:41
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!! » dancingstar, posted by Larry Hoover on January 24, 2005, at 11:41:08
Hey Lar,
Thank you very much for explaining in plain English that it is safe to take the combination of Prozac and Benadryl.
Many people here are taking that combo. Because I don't know the chemical ingredient of the drug, may I ask you if it is also safe to take Prozac with Claritin D, which is also popular on this site?
Thanks again. It is so hard to get straight information, and I really appreciate your help
:-)!
Posted by jubilee on January 24, 2005, at 14:11:19
In reply to Re: MAYBE WE SHOULD RETHINK THE BENADRYL GUYS!!! » dancingstar, posted by Larry Hoover on January 24, 2005, at 11:41:08
5 months ago or more when I first came to this board a dr like person, very sientific, talked about how the withdrawal has a major effect on your hystamines( excuse poor spelling ) levels and many mentioned how their whole bodies iched so I assume thats why the benadryl was brought up.
Well, i came down slow , 5 mths and off of effexor completly for a couple weeks and my nose iches so bad, I cant imagine the whole body, but I discovered that my nose spray would take away the headaches I was getting from the w/d and I now using it on my nose which stops the iching. .
I have been so frustrated with the length of time it takes to get this drug out of your system . Personally the worst part for me has been the angry outbursts and I am still dealing with . a friend came over and prayed for me I have been doing better about the anger and have been able to want to go to bed for 4 nights now. I personally don't know how far out I would go with my anger if I didnt have some xanex.
I had every side affect from effexor but the high blood pressure. I have fought going to bed and to sleep for 4 years now, so for me to say I have wanted and been going to bed early is a miricle. I have had hypermania , agitation and anxiety since I ws first put on effexor . I have destroyed my vision from taking it and I have been having memory problems this last year . I so pray I completely recover from taking this drug and that I dont find I have a major liver problem for it or something . I wonder how many more weeks until I go back to the self controlled person I was 4 years ago. and hoping soon to be able to go off the xanex.
Posted by corafree on January 24, 2005, at 16:10:38
In reply to My ichy nose is driving me nuts, posted by jubilee on January 24, 2005, at 14:11:19
Jubilee - Memory impairment from Effexor-XR ... I have memory impairment, but cannot be sure from Eff-XR, as also benzos can cause it, as well as trazodone which take for sleep, as well as many years on diff' ADs, and also having my head beaten on the floor in 2000. I currently am feeling like I may have ADD or ADHD. I took the test, said 89% chance had it. But, do I want another pill? I am really, really alone and often go w/o contact w/ another person for 3-4 days. I don't dare change anything until I am in a supportive environment. Hope AD studies re: memory/Alzheimer's come to light soon. cf
Posted by eeyorena on January 24, 2005, at 16:27:06
In reply to Re: Benadryl is safe! » corafree, posted by Larry Hoover on January 24, 2005, at 5:56:30
If you take the AD, Parnate, pure Benadryl should be safe according to the Drug Interaction Checker.
The following OTC drugs should NOT be taken with Parnate or they can cause reactions of MAJOR severity.
-Any Benadryl Allergy products (Allergy & Sinus, Benadryl Allergy & Cold, Benadryl Allergy Sinus Headache)
-Claritan-D or Claritan-D 24 hour
-Chlor-Trimeton Allergy Decongestant and Chlor-Trimeton Nasal DecongestantThese over the counter drugs should NOT be combined with the anti-depressant, Parnate.
Posted by eeyorena on January 24, 2005, at 16:30:13
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE » FaithT, posted by corafree on January 24, 2005, at 12:02:19
cf--
Did your doc ever have you on an MAOI? Just curious.
E-
Posted by dancingstar on January 24, 2005, at 16:44:45
In reply to RE: NEW THREAD IS AT BOTTOM OF THIS PAGE, posted by FaithT on January 24, 2005, at 12:56:50
If someone checks in on a site to see if anyone has had success on Effexor and they see that a lot of people are having problems as a result of having taken it, I think that tells them that they might want to be cautious before they begin to take the drug.
The problem seems to be that the doctors have been telling patients that Effexor is safe. It is widely prescribed. People need a place to find out the truth. It appears to me that many of us are relieved to find out that there are others that have had similar experiences to our own, and that it didn't turn out that Effexor was as safe as we were told that it was.
Everyone has been telling people how wonderful the drug is, and it's nice to be able find out that it is a potentially dangerous drug before one takes it, not some time down the line after it's already in one's body.
Posted by dancingstar on January 24, 2005, at 16:46:06
In reply to Re: Benadryl is safe for some and in certain forms, posted by eeyorena on January 24, 2005, at 16:27:06
...as usual, thank you :-)
Posted by not2late4u on January 24, 2005, at 21:36:03
In reply to RE: NEW THREAD IS AT BOTTOM OF THIS PAGE, posted by FaithT on January 24, 2005, at 12:56:50
FaithT, GREAT! I think its so important to have a big picture of Effexor. As you know Im withdrawing now, because its just time for me and I did have some fatigue issues, but I'd take it again if needed to. Thanks for posting a new thread, its needed.
Posted by not2late4u on January 24, 2005, at 21:39:20
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE, posted by FaithT on January 24, 2005, at 4:19:29
FaithT, here's another thread you know about thought it'd be good for those who are withdrawing or want to: "Effexor Withdraw, Tapering Off - CAN BE DONE" is another positive post. God Bless you FaithT!
Posted by not2late4u on January 24, 2005, at 21:41:22
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE » FaithT, posted by corafree on January 24, 2005, at 12:02:19
CF, sounds like youre doing better. Really happy for you. Anxiety was my primary dx, depression came afterwards for me to. Anyways, sounds like we might have that in common :) Renee
Posted by not2late4u on January 24, 2005, at 21:48:53
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE, posted by medhed on January 24, 2005, at 12:20:22
Medhead, Sorry for your experience and glad you were able to get the help you needed. I think, as others do, thats its just as important to know the POSITIVE experiences as it is the negative, so thank you for letting us know that you know of others who sweat by it. God Bless, Renee
Posted by FaithT on January 24, 2005, at 23:52:53
In reply to Has anyone had success on Effexor » FaithT, posted by dancingstar on January 24, 2005, at 16:44:45
Bebe~
In all due respect, people also need a place to find positive experiences on the drug. Do they not? People do need hope, Bebe, and not every single person feels lied to by their Dr., or tainted by Effexor.
I do not wish to debate this. So, I kindly ask you to not post directly to me, and I will do the same.
Faith~
Posted by FaithT on January 24, 2005, at 23:57:55
In reply to RE: NEW THREAD IS AT BOTTOM OF THIS PAGE » FaithT, posted by not2late4u on January 24, 2005, at 21:36:03
Thanks so much Renee~
A agree, and I think that there needs to be a balance of postive and negative about Effexor.
I found your post,and I think it's awsome that your journaling your withdrawl. I posted to you there,as well.
You know I'm behind you...You will get through this,and be just fine.
Many hugs, Faith~
Posted by corafree on January 25, 2005, at 0:23:41
In reply to RE: NEW THREAD - POSITIVE EFFEXOR EXPERIENCE, posted by eeyorena on January 24, 2005, at 16:30:13
You know what, I don't think so. I thought I'd been on everything out there, but never an MAOI. Can I ask you; why do you think they were never suggested to me, and for what form of depression are they indicated? Tks cf
Posted by dancingstar on January 25, 2005, at 2:14:32
In reply to Re: Has anyone had success on Effexor » dancingstar, posted by FaithT on January 24, 2005, at 23:52:53
Well, Faith, you have certainly told me. I feel appropriately chastised.
(hanging my head in shame.)
Posted by Dr. Bob on January 25, 2005, at 8:11:11
In reply to Re: Has anyone had success on Effexor » FaithT, posted by dancingstar on January 25, 2005, at 2:14:32
> Well, Faith, you have certainly told me.
If someone asks you not to post to them, please don't post to them.
If you or others have questions about this or about posting policies in general, please see the FAQ:
http://www.dr-bob.org/babble/faq.html#harassed
Follow-ups regarding these issues should be redirected to Psycho-Babble Administration. They, as well as replies to the above post, should of course be civil.
Thanks,
Bob
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