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Dr. Bob is Robert Hsiung, MD,
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Posted by KaraS on June 30, 2004, at 1:21:31
In reply to Re: Efferox side effects - motivation, posted by Geekgirl on June 28, 2004, at 0:51:00
Effexor has done nothing for my motivation either though it has helped a bit with depression. I'm not sure if it has made my motivation worse but it certainly hasn't helped. The SSRIs do have that emotional leveling effect. I know that Effexor is supposed to have some noradrenergic activity but only at the much higher dosages and then not even that much. The way you described yourself is exactly how I feel - so sluggish and apathetic. I can make jokes and be very social so people don't know that I'm so unmotivated. I'm in the process of getting off of Effexor. I'm determined to find something else that will give me some energy and drive. The way I've been living is just not cutting it.
Posted by livingjuliet on June 30, 2004, at 3:06:05
In reply to Anyone had success on Effexor XR? , posted by jp on October 24, 1999, at 14:59:14
Has anyone had the experience of being hungrier than normal when going off of Effexor? I feel a little sick because I haven't taken the medicine in a week (I've been gradually reducing the dosage the past few months), and so it makes me feel slightly sick. Well, eating makes that sick feeling that I know is because of withdrawal go away, so I have found myself eating a LOT more than usual. I hate this... I'm hoping it goes away SOON.
Posted by Shyla on June 30, 2004, at 8:32:30
In reply to Re: Efferox side effects - motivation, posted by KaraS on June 30, 2004, at 1:21:31
> Effexor has done nothing for my motivation either though it has helped a bit with depression. I'm not sure if it has made my motivation worse but it certainly hasn't helped. The SSRIs do have that emotional leveling effect. I know that Effexor is supposed to have some noradrenergic activity but only at the much higher dosages and then not even that much. The way you described yourself is exactly how I feel - so sluggish and apathetic. I can make jokes and be very social so people don't know that I'm so unmotivated. I'm in the process of getting off of Effexor. I'm determined to find something else that will give me some energy and drive. The way I've been living is just not cutting it.
If you haven't tried it already, you might want to take Zoloft. I found at 150 mgs. I had more energy, than I knew what to do with. It made me extremely social too. The negative side of it was that I had difficulty focusing on doing my job.
Posted by Shyla on June 30, 2004, at 8:44:22
In reply to Re: Help-any ideas from anyone, been around the block, posted by KaraS on June 30, 2004, at 1:06:48
Kara, I have been on Zoloft, Wellbutrin, Remeron, now Effexor. It does take patience, and a willingness to give each med a chance to really find out if it works, and what the side effects are, and if you can live with those side effects. I have been on 75 mgs. of Effexor for 7 mos. now. I like it because it has greatly reduced my anxiety, stabilized my moods, and is really helping me enjoy life and laugh again. I don't take things so seriously. The couple of side effects I do experience are trouble sleeping, but Gabatril and Ambien have taken care of that, and sexual side effects. I'm now experimenting with a day off of Effexor coupled with Wellbutrin on a day of anticipating lovemaking. It has seemed to help part of the time, not always. So, the long and the short of it is that I'm overall happy with Effexor. I am very open and upfront with my doctor about my experiences and concerns, and together we experiment with alternatives to improve things. I hope this helped.
Posted by KaraS on June 30, 2004, at 18:21:53
In reply to Re: Efferox side effects - motivation » KaraS, posted by Shyla on June 30, 2004, at 8:32:30
I was on Zoloft for over 2 years. It did nothing for me besides make me an emotional zombie and ensure no panic attacks. Thanks though.
Posted by KaraS on June 30, 2004, at 18:50:09
In reply to Re: Help-any ideas from anyone, been around the block » KaraS, posted by Shyla on June 30, 2004, at 8:44:22
> Kara, I have been on Zoloft, Wellbutrin, Remeron, now Effexor. It does take patience, and a willingness to give each med a chance to really find out if it works, and what the side effects are, and if you can live with those side effects. I have been on 75 mgs. of Effexor for 7 mos. now. I like it because it has greatly reduced my anxiety, stabilized my moods, and is really helping me enjoy life and laugh again. I don't take things so seriously. The couple of side effects I do experience are trouble sleeping, but Gabatril and Ambien have taken care of that, and sexual side effects. I'm now experimenting with a day off of Effexor coupled with Wellbutrin on a day of anticipating lovemaking. It has seemed to help part of the time, not always. So, the long and the short of it is that I'm overall happy with Effexor. I am very open and upfront with my doctor about my experiences and concerns, and together we experiment with alternatives to improve things. I hope this helped.
Shyla,
I have been on many meds for adequate periods of time but unfortunately none has been great for me so far. The tricyclics have helped me sleep and totally gotten rid of my panic disorder/agoraphobia several years ago but none of these meds has adequately addressed my depression. Effexor has been the best so far (with virtually no side effects) but I know that I could be doing a lot better. I feel that I'm moving in the right direction though. I know that I need some serotonin assistance to protect against panic attacks but mostly I need NE and dopamine for energy, motivation and zest for life. My quest for the right medication or combination of medicines is at least going to be more intelligently targeted going forward.I hope you have continued success on the Effexor. Have you tried Ginkgo for the sexual side effects? A lot of people have had great success with that!
Posted by Shyla on July 1, 2004, at 8:31:17
In reply to Re: Help-any ideas from anyone, been around the block, posted by KaraS on June 30, 2004, at 18:50:09
> > Kara, I have been on Zoloft, Wellbutrin, Remeron, now Effexor. It does take patience, and a willingness to give each med a chance to really find out if it works, and what the side effects are, and if you can live with those side effects. I have been on 75 mgs. of Effexor for 7 mos. now. I like it because it has greatly reduced my anxiety, stabilized my moods, and is really helping me enjoy life and laugh again. I don't take things so seriously. The couple of side effects I do experience are trouble sleeping, but Gabatril and Ambien have taken care of that, and sexual side effects. I'm now experimenting with a day off of Effexor coupled with Wellbutrin on a day of anticipating lovemaking. It has seemed to help part of the time, not always. So, the long and the short of it is that I'm overall happy with Effexor. I am very open and upfront with my doctor about my experiences and concerns, and together we experiment with alternatives to improve things. I hope this helped.
>
>
> Shyla,
> I have been on many meds for adequate periods of time but unfortunately none has been great for me so far. The tricyclics have helped me sleep and totally gotten rid of my panic disorder/agoraphobia several years ago but none of these meds has adequately addressed my depression. Effexor has been the best so far (with virtually no side effects) but I know that I could be doing a lot better. I feel that I'm moving in the right direction though. I know that I need some serotonin assistance to protect against panic attacks but mostly I need NE and dopamine for energy, motivation and zest for life. My quest for the right medication or combination of medicines is at least going to be more intelligently targeted going forward.
>
> I hope you have continued success on the Effexor. Have you tried Ginkgo for the sexual side effects? A lot of people have had great success with that!Kara, no I haven't tried Ginkgo, but I will. Do you know how many mgs. are effective? Thank you for the suggestion. Have you tried Wellbutrin in combination with Effexor for the dopamine and engergy boost?
>
>
Posted by jenn007 on July 1, 2004, at 9:10:10
In reply to Re: New to Effexor XR, my side effects, anyone else?, posted by Cindy W on August 28, 2000, at 21:57:24
I read Cindy W's message about effexor and i just wanted to say that i am experiencing all of those things to. I am on 75mg for about 5-6 weeks now and am just worn out. i cant get enough sleep. which is really not good for getting anything done. as a new mom, i really need my energy. the dreams are crazy, the metal taste i sometimes get, i sweat all the time and no interest in sex. however, no more panic attacks and i am definately more tolerant of things that used to stress me out. any suggestions for how to get my energy back? does that part wear off? the headaches are a bear sometimes, but the fatigue is worse...please help
Posted by Shyla on July 1, 2004, at 10:20:12
In reply to Re: New to Effexor XR, my side effects, anyone els, posted by jenn007 on July 1, 2004, at 9:10:10
> I read Cindy W's message about effexor and i just wanted to say that i am experiencing all of those things to. I am on 75mg for about 5-6 weeks now and am just worn out. i cant get enough sleep. which is really not good for getting anything done. as a new mom, i really need my energy. the dreams are crazy, the metal taste i sometimes get, i sweat all the time and no interest in sex. however, no more panic attacks and i am definately more tolerant of things that used to stress me out. any suggestions for how to get my energy back? does that part wear off? the headaches are a bear sometimes, but the fatigue is worse...please help
>Although you've been on Effexor for 5-6 wks, your system may still be adjusting. If you can tolerate the side effects a little more, they should eventually go away. Wellbutrin coupled with Effexor might give you more energy. Good luck!
Posted by jenn007 on July 1, 2004, at 10:48:55
In reply to Re: New to Effexor XR, my side effects, anyone els, posted by Shyla on July 1, 2004, at 10:20:12
> > I read Cindy W's message about effexor and i just wanted to say that i am experiencing all of those things to. I am on 75mg for about 5-6 weeks now and am just worn out. i cant get enough sleep. which is really not good for getting anything done. as a new mom, i really need my energy. the dreams are crazy, the metal taste i sometimes get, i sweat all the time and no interest in sex. however, no more panic attacks and i am definately more tolerant of things that used to stress me out. any suggestions for how to get my energy back? does that part wear off? the headaches are a bear sometimes, but the fatigue is worse...please help
> >
>
> Although you've been on Effexor for 5-6 wks, your system may still be adjusting. If you can tolerate the side effects a little more, they should eventually go away. Wellbutrin coupled with Effexor might give you more energy. Good luck!
>
Thanks - My doctor told me try a vitamin and more sleep (duh- i cant get outta bed). I am gonna try it out for another month and see. Maybe then I can get him to try Wellbutrin too. thanks again.
Posted by Corafree on July 1, 2004, at 16:53:02
In reply to Re: New to Effexor XR, my side effects, anyone els, posted by jenn007 on July 1, 2004, at 10:48:55
Maybe you are actually withdrawing and your body is telling you that you need more ... maybe another dose midday ... and maybe even one more late day. I metabolize extended release medication quickly. Does anyone else out there? I could go back to plain Effexor, but there is something about the Effexor-XR that lifts my depression a bit more. Still, like I said, it would never last the whole day for me. Just a thought for you to consider in wondering why you are so fatigued! Best wishes! Corafree
Posted by LynnM. on July 1, 2004, at 18:05:34
In reply to Re: Efferox side effects - motivation, posted by Geekgirl on June 28, 2004, at 0:51:00
Your thoughts are/were mine, exactly! I posted earlier that I had problems with motivation, too. And, didn't really care if things got done or not, or how people felt about it or me. I'm a teacher in a public school system!
With coming off the Effexor (best decision for ME), I am gradually getting re-motivated, though it is taking some time. I still sometimes have to make myself do things, but I do notice improvement in myself.
Like you...sure, I felt better~euphoric, as a matter of fact, but I was getting nothing of importance done, and could've cared less. I've never been a "lazy" person, so...I attributed my behavior to the medicine.
Posted by LynnM. on July 1, 2004, at 18:12:56
In reply to Going off of Effexor, posted by livingjuliet on June 30, 2004, at 3:06:05
> Has anyone had the experience of being hungrier than normal when going off of Effexor? I feel a little sick because I haven't taken the medicine in a week (I've been gradually reducing the dosage the past few months), and so it makes me feel slightly sick. Well, eating makes that sick feeling that I know is because of withdrawal go away, so I have found myself eating a LOT more than usual. I hate this... I'm hoping it goes away SOON.
I am gradually coming off Effexor, too. My appetite has decreased some, I'm finding. Which is really good, because I was REVENOUS while taking it! I've also found I do get a little sick to my stomach lately, but I know that's a withdrawal side effect. Haven't eaten anymore, have actually eaten less!
I'm telling y'all...this has been the best info. source for talking with others who have had same problems with Effexor/anti-depressants as me. I'm almost out of my last bottle of Effexor, and I'm stretching it out as long as I can, taking about 37 mg. every 4 days. Brain zaps and everything!: :-)
Posted by lorily on July 1, 2004, at 18:39:50
In reply to Re: Going off of Effexor, posted by LynnM. on July 1, 2004, at 18:12:56
I can't understand why you would be taking Effexor every 4 days. I think you would be prolonging your withdrawals rather than getting off of them. I've read several people's posts about it and this is the first I've heard of it.
I'm at 37.5, started there, then went up to 75 last Sept when I was having great things happen and had no reaction to them. 4-5 weeks ago cut it down, I've stopped taking depakote since Sunday night and very nervous about stopping Effexor.
As for anyone with the sexual side effects problem, my doctor prescribed viagra (yes I'm female) and it does work. It increases the flow of blood to the genitals, making us more sensitive. My problem was not lack of desire, but lack of response. I hope this helps everyone.
Posted by KaraS on July 1, 2004, at 19:10:54
In reply to Re: Help-any ideas from anyone, been around the block, posted by Shyla on July 1, 2004, at 8:31:17
> > > Kara, I have been on Zoloft, Wellbutrin, Remeron, now Effexor. It does take patience, and a willingness to give each med a chance to really find out if it works, and what the side effects are, and if you can live with those side effects. I have been on 75 mgs. of Effexor for 7 mos. now. I like it because it has greatly reduced my anxiety, stabilized my moods, and is really helping me enjoy life and laugh again. I don't take things so seriously. The couple of side effects I do experience are trouble sleeping, but Gabatril and Ambien have taken care of that, and sexual side effects. I'm now experimenting with a day off of Effexor coupled with Wellbutrin on a day of anticipating lovemaking. It has seemed to help part of the time, not always. So, the long and the short of it is that I'm overall happy with Effexor. I am very open and upfront with my doctor about my experiences and concerns, and together we experiment with alternatives to improve things. I hope this helped.
> >
> >
> > Shyla,
> > I have been on many meds for adequate periods of time but unfortunately none has been great for me so far. The tricyclics have helped me sleep and totally gotten rid of my panic disorder/agoraphobia several years ago but none of these meds has adequately addressed my depression. Effexor has been the best so far (with virtually no side effects) but I know that I could be doing a lot better. I feel that I'm moving in the right direction though. I know that I need some serotonin assistance to protect against panic attacks but mostly I need NE and dopamine for energy, motivation and zest for life. My quest for the right medication or combination of medicines is at least going to be more intelligently targeted going forward.
> >
> > I hope you have continued success on the Effexor. Have you tried Ginkgo for the sexual side effects? A lot of people have had great success with that!
>
> Kara, no I haven't tried Ginkgo, but I will. Do you know how many mgs. are effective? Thank you for the suggestion. Have you tried Wellbutrin in combination with Effexor for the dopamine and engergy boost?
> >
> >I'm not sure how much Ginkgo you should take. (It's not a good idea to take if you're on any kind of blood-thinning medication or if you take aspirin regularly.) You could post over on the Pscyho-Babble Alternative board. There are some incredibly knowledgable people over there who would be able to give you the details.
I tried Wellbutrin but unfortunately I had an allergic reaction to it. I was really disappointed because I thought that might be a really good combo for me too.
Posted by gbtbag on July 1, 2004, at 19:17:44
In reply to Re: Efferox side effects, posted by megamufn on March 14, 2003, at 6:12:47
i want to come off Effexor XR as well, as i feel it's no longer helping me when it comes to reducing anxiety.
i'm very aware that there is a tendency to expect too much from these drugs. then again, only we can tell whether or not we're really getting any benefit. for me, as it did with Prozac, Effexor doesn't work anymore.
i tried increasing the dosage from 150mg to 225mg but all it did was worsen the side effect i detest, which is excessive sweating.
i'm hoping to get my County psychiatrist to switch me to something i haven't tried--Welbutrin, perhaps--as Prozac and Effexor are the only drugs i've been able to tolerate so far. Paxil, Serzone and Zoloft all had real downsides or just plain didn't work.
Posted by esskay on July 1, 2004, at 21:49:41
In reply to Re: Going off of Effexor, posted by lorily on July 1, 2004, at 18:39:50
I'm day 5 coming off Effexor 75mg. I was on it for about a year-- I went on because I was trying to balance law school and wedding planning across state lines and family. My main problem was sleep, which was cured by 25mg of trazadone, but then the doctor wanted to put me on the Effexor as well, which didn't make any difference. I also have "fibromyalgia" which no one believes in, and I'm supposedly atypical because I push right through the pain and get on with things-- sleep is my main concern, which, if I don't get it, gives rise to anxiety about not sleeping. The trazadone has fixed this for me. I think maybe the doctor thought that the Effexor would help the pain, but it is not clear what links it has with helping the fibromyalgia [as an aside, I've found that good old exercise is a great help].
So: I've graduated from school a month ago and have been booted from the insurance and my doctor. I cannot afford the $100+ per month of the Effexor nor could I get a response from the doctor who put me on the med, since I was no longer a university patient. Also, being without insurance for the time being, I cannot afford to "get to know" a new doctor to come up with a new game plan that will include going off Effexor.
So I figured I'd take matters into my own hands and just didn't pick up my refill. I had been without for a few days at a time before and would feel dizzy, with upset stomach, electric shock sensations and a thrushing/wooshing sound in my ears. So, I bravely (stupidly? not sure) just quit to see if I could brave it and see how long the withdrawal lasts.
An aside: this is a terrible medication. It was improperly prescribed for me I'm sure becuase after 5 days I'm having no anxiety, no mood swings that worry me, no sleep problems. It is terrible to prescribe a drug to people that is so hard to come off of, especially in the university setting where people are transient and may not be able to have consistent monitoring because of breaks, graduation, etc.
Anyway, on day 5 I'm no longer sick to my stomach. I'm having great dreams (colorful) although I've read from others' postings that nightmares are common. I still have occasional thrushing in my ears and the electric shock sensataions are less frequent.
I've read that those who go off higher dosages have worse trouble, but those that prolong the tapering feel the withdrawal effects just as much.
Does anyone know of any clinical trials that have tracked this withdrawal? In terms of how long the weird side effects are "supposed to" last and/or how lng they actually do when coming off 75mg?
Posted by Corafree on July 2, 2004, at 1:29:14
In reply to Re: Going off of Effexor, posted by esskay on July 1, 2004, at 21:49:41
See page 40 @ http://www.fda.gov/cder/foi/label/2003/20699se1-022_Effexor_lbl.pdf
Posted by LynnM. on July 2, 2004, at 1:55:27
In reply to Re: Going off of Effexor, posted by lorily on July 1, 2004, at 18:39:50
> I can't understand why you would be taking Effexor every 4 days. I think you would be prolonging your withdrawals rather than getting off of them. I've read several people's posts about it and this is the first I've heard of it.
I'm trying to get OFF of Effexor. I don't want to just quit cold turkey. I'm gradually slowing down to decrease intensity of the withdrawal symptoms I'm experiencing: headache, nausea, brain zaps, sporadic itching.
Posted by lorily on July 2, 2004, at 6:06:46
In reply to Re: Going off of Effexor, posted by LynnM. on July 2, 2004, at 1:55:27
I am also a recovering addict. I know that when you consistly wean yourself off of substances(bringing the daily dose lower and lower) your body adjusts to the lower levels, slowly eliminating the substance from your body until you are able to do without it.
Now, going 4 days without anything, your body is withdrawing, going through your torture, then you feed it a mega dose of the substance it's craving, bringing the dependancy right back. And then you torture it again for 4 days instead of letting your body heal. I'm sure that each day you feel a little better then the last, that's your body getting better, getting used to it not being there, then you jump it up again. Effexor has a short half-life, that's why we feel the withdrawals so severely, it's leaving quickly, so I can't understand why you would torture yourself over and over again.
I'm not a doctor, but I know all about phsyical dependancy. I'd really talk to your doctor about this method you're using.
Posted by Dr. Bob on July 3, 2004, at 16:03:27
In reply to Re: Efferox side effects - motivation, posted by LynnM. on July 1, 2004, at 18:05:34
Posted by donna0099 on July 2, 2004, at 20:05:18
> my dr is taking me off paxil but i think it is being done to fast i took 1/2of 20mg for ten days then had to take 1/2 of 20 every second day then none for a week then he 's gonna put me on a trial drug "duloxetine" anyone heard of it? but the withdrawal is pretty brutal nausea diareeha, sleep disturbanced, zaps are beyond , crying spells , i have to come off paxil becuase i've gained alot of weight on it and i now have type 2 diabetes and very high cholesterol so paxil makes me eat and it has to go in order for me to get my health back . i am 44 year old female but i feel 90 .... and fat
Posted by KaraS on July 3, 2004, at 20:13:33
In reply to Re: Efferox side effects - motivation « donna0099, posted by Dr. Bob on July 3, 2004, at 16:03:27
That does seem like a short time to try to get off of Paxil. These doctors have no clue what we go through trying to withdraw from some of these meds! Adding in another med with serotonergic effect can help a lot. Duloxetine has some of that so maybe your doctor will allow you to start on it before you're completely off of the Paxil. You are lucky that he/she is going to start you on that drug. Many people, including lots of posters on this board, are waiting for that drug to come out. It's brand name is Cymbalta and you will find several posts here about it. Please let us know what your experience is with it.
Posted by theo on July 4, 2004, at 7:47:35
In reply to Re: Efferox side effects - motivation « donna0099, posted by Dr. Bob on July 3, 2004, at 16:03:27
Please let me know how the duloxetine works for you. It's supposed to finally be out to the public in September but would be interested to here your experience since you get to try it before its release.
Posted by donna0099 on July 4, 2004, at 16:45:24
In reply to Re: Efferox side effects - motivation, posted by KaraS on July 3, 2004, at 20:13:33
> That does seem like a short time to try to get off of Paxil. These doctors have no clue what we go through trying to withdraw from some of these meds! Adding in another med with serotonergic effect can help a lot. Duloxetine has some of that so maybe your doctor will allow you to start on it before you're completely off of the Paxil. You are lucky that he/she is going to start you on that drug. Many people, including lots of posters on this board, are waiting for that drug to come out. It's brand name is Cymbalta and you will find several posts here about it. Please let us know what your experience is with it.
Hi thanks for replying! Why do you say i'm lucky he is suggesting Cymbalta, i am in Canada and it has not been approved here yet... i very nervous about taking it, but i know i must come off the paxil can you enlighten me on the Cymbalta , has it been available for awhile anywhere, i am going to participate in a study,,, ( with duloxetine ) feel like a guinea pig.
Posted by KaraS on July 4, 2004, at 18:47:25
In reply to Re: Efferox side effects - motivation, posted by donna0099 on July 4, 2004, at 16:45:24
> > That does seem like a short time to try to get off of Paxil. These doctors have no clue what we go through trying to withdraw from some of these meds! Adding in another med with serotonergic effect can help a lot. Duloxetine has some of that so maybe your doctor will allow you to start on it before you're completely off of the Paxil. You are lucky that he/she is going to start you on that drug. Many people, including lots of posters on this board, are waiting for that drug to come out. It's brand name is Cymbalta and you will find several posts here about it. Please let us know what your experience is with it.
>
> Hi thanks for replying! Why do you say i'm lucky he is suggesting Cymbalta, i am in Canada and it has not been approved here yet... i very nervous about taking it, but i know i must come off the paxil can you enlighten me on the Cymbalta , has it been available for awhile anywhere, i am going to participate in a study,,, ( with duloxetine ) feel like a guinea pig.Cymbalta (duloxetine) is not available anywhere yet to my knowledge but a lot of people in the U.S. (and probably elsewhere) have been anxiously awaiting its approval. It has the potential to be a very powerful antidepressant because it equally effects serotonin and NE (noradrenaline). The only other antidepressant (not counting any APs) that is approved in the U.S. that can do that now is Effexor but only in the higher dosage range and even then it is still more of a serotonergic medication.
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