Posted by SLS on December 19, 2011, at 8:06:37
In reply to Seeking insight on treatment resistant depression, posted by Amorphous on December 19, 2011, at 3:07:56
I have no answers for you because I haven't found answers for me. Your case profile greatly resembles mine. The only period of remission that I experienced was brought about by taking a combination of Parnate and desipramine. If you haven't tried a TCA + MAOI combination, you might want to take a serious look at it. My brief responses to antidepressants last for no longer than three days, after which no improvement can be recaptured regardless of dosage or time. I have the same concerns regarding DBS. I worry that my brain will quickly compensate for and relapse during treatment. Some people report responding to an opioid known as buprenorphine (Subutex). It is used for pain and to combat heroin addiction. It is an interesting drug. I am interested in the ketamine studies that demonstrate a very rapid antidepressant response, often within hours. It has been described as a kick-start that will make other antidepressants work better.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1005215
URL: http://www.dr-bob.org/babble/neuro/20110604/msgs/1005220.html