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Re: SSRIs work by numbing emotions? - Myth?

Posted by Hordak on January 15, 2019, at 15:01:39

In reply to SSRIs work by numbing emotions? - Myth?, posted by SLS on January 15, 2019, at 6:20:08

NRIs have some downstreaming effects which boost dopamine transmission.
That is also true for 5HT2 and 5HT3 antagonists...

That is why the combo Sertraline + Nortriptyline is so effective. Another good one is Clomipramine.

> what happens to these effects when SNRIs (Effexor, Pristiq, Cymbalta? are applied? I have responded better to Effexor and Cymbalta (SNRI) than to Paxil and Prozac (SSRI). I experienced not apathy and amotivation at all with SNRIs.


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poster:Hordak thread:1102788
URL: http://www.dr-bob.org/babble/20181024/msgs/1102802.html