Posted by ed_uk2010 on July 22, 2018, at 11:08:23
In reply to Fetzima, the pit of despair, posted by TriedEveryMedication on July 15, 2018, at 12:13:37
>I had to quit the desipramine + prozac because my resting heart rate was 129 :/ )
So, how well did this combination work (or not work)? Did you have any adverse effects apart from increased heart rate?
Sinus tachycardia at rest is extremely typical of desipramine. And with fluoxetine, you'd want to stick to very low doses of desipramine due to the metabolic interaction.
If an ECG/EKG showed that it was just the typical sinus tachycardia and nothing more serious, you could consider an add on, since sinus tachy isn't particularly difficult to treat.
First though, it would be worthwhile reducing the dose of desipramine and finding out whether you can maintain a response at a lower dose without tachycardia. The dose may be very low, because fluoxetine interacts - it's not like taking desipramine alone.
poster:ed_uk2010
thread:1099606
URL: http://www.dr-bob.org/babble/20180521/msgs/1099818.html