Posted by SLS on May 11, 2015, at 9:28:48
In reply to Bipolar depression - need med suggestions, posted by momandwife on May 10, 2015, at 21:18:44
I don't think Seroquel at such a low dose would function as an antidepressant nor an antimanic drug. You might consider switchiing to Abilify, a drug which is generally deemed to have antidepressant effects. From my own experience, Saphris has antidepressant potential. I take both for bipolar depression. Each drug has different properties that, for me, seem to be complementary. Neither drug has produced flattened affect.
Latuda has been a disappointing drug for the most part. Although your husband experienced unacceptable anger episodes with it, I am encouraged for others that it might have antidepressant properties after all.
Some people need 300 mg/day of Lamictal to receive benefit for depression. As important as Lamictal can be in one's treatment, it is my impression that it seldom works by itself.
I would like to suggest Trileptal as a mood stabilizer since it has anti-manic, anti-impulsive, and ant-anger effects. I don't know if it would allow you to return to Latuda and prevent anger as a side effect, but that might be something to keep in mind if you become frustrated with future drug trials.
Some people with bipolar depression respond to a combination of Wellbutrin, Lamictal, and Abilify. Wellbutrin makes my bipolar depression worse, so other drugs are being used in its place. Also, a combination of Lamictal and Trileptal can be helpful for bipolar mixed states.
Regarding vitamin D:
"The main consequence of vitamin D toxicity is a buildup of calcium in your blood (hypercalcemia), which can cause poor appetite, nausea and vomiting. Weakness, frequent urination and kidney problems also may occur.
Treatment includes the stopping of excessive vitamin D intake. Your doctor also may prescribe intravenous fluids and medications, such as corticosteroids or bisphosphonates.
Taking 50,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day."
Have you tried Pristiq in combination with Wellbutrin and Trileptal?
As you can see, people here have offered alternative treatments. I hope that gives you hope.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1078863
URL: http://www.dr-bob.org/babble/20150407/msgs/1078875.html