Posted by Deahoidar on March 24, 2015, at 14:32:40
In reply to Re: Discouraged after reading book on resistant cases » Deahoidar, posted by Robert_Burton_1621 on March 24, 2015, at 10:01:47
> > I have a considerable library on the subject.
>
> Deahoidar. I'm sorry to hear of your unfortunate, and (it seems) clinically brutal, experience with DBS. I am very interested in reading any citations to research you may be minded to share.
>
>As you may be aware, clinical trials with negative outcomes are very rarely published. Some articles worth reviewing are:
Unusual Complications of Deep Brain Stimulation.
Neurosurg Rev
DOI 10.1007/s10143-014-0588-9A Randomized Sham-Controlled Trial of Deep
Brain Stimulation of the Ventral Capsule/Ventral
Striatum for Chronic Treatment-Resistant
Depression
http://dx.doi.org/10.1016/j.biopsych.2014.11.023And especially,
Deep Brain Stimulation for Treatment-resistant Depression:
Systematic Review of Clinical Outcomes
(T. Morishita et al)
Neurotherapeutics
DOI 10.1007/s13311-014-0282-1There are many more, but that's a start. What I can tell you is that DBS is significant brain surgery with significant risks. And the benefits are far from certain. Would I do it again? Probably not. But then, I would probably be dead. I figured why not.
poster:Deahoidar
thread:1077033
URL: http://www.dr-bob.org/babble/20150223/msgs/1077787.html