Posted by SLS on January 4, 2014, at 7:21:23
In reply to please advice about my next move please im stuck, posted by Jeroen on January 4, 2014, at 5:23:48
> > please advice about my next move please im stuck
>
> Unfortunately, the only thing I can think of is for you to present your doctors with information that they obviously don't have.
>
> I'll see what I can do. In the meantime, I gave you 2 articles for your doctors to read.Try these, Jeroen:
- Scott------------------------------------------------
Google Search: https://www.google.com/#q=minocycline+schizophrenia
http://www.ncbi.nlm.nih.gov/pubmed/19895780
http://www.ncbi.nlm.nih.gov/pubmed/19855900
http://www.ncbi.nlm.nih.gov/pubmed/18991666
http://www.trialsjournal.com/content/14/1/406
-----------------------------------------------------
Minocycline:
1. Is neuroprotective.
2. Reduces brain inflammation
3. Reduces the number of glutamate receptors.
4. Demonstrates antidepressant and antipsychotic properties in mouse models.
5. Is reported to act synergistically with noradrenergic antidepressants to treat depression - desipramine (but not fluoxetine).
6. Is reported to act synergistically with NMDA antagonists.
7. Reduces glutamate excitotoxicity by reducing the formation of quinolic acid, a NMDA agonist.
8. Reduces mitochondrial release of cytochrome C.
9. Modulates several signaling pathways.
10. Reduces microglial activation.
11. Has been reported anecdotally to successively treat depression.
12. Reduces the expression of lipopolysaccharide-induced pro-inflammation cytokines, an effect that acts as an antidepressant in animal models.
13. Increases neurite growth in response to nerve growth factor (NGF).
14. Inhibits high levels of PKC and GSK-3 alpha;
15. Decreases nitric oxide synthetase, thereby reducing free radicals which damage neurons and glia.
16. Reduces glutamate release.----------------------------------------------------
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1057724
URL: http://www.dr-bob.org/babble/20140104/msgs/1057758.html