Posted by sk85 on October 15, 2013, at 10:26:45
Hello! Haven't written here for some time. I'm interested to hear about experiences relating to naltrexone (low-dose) and its effects on anhedonia.
I'm currently taking 50 mg of sertraline (Zoloft) for depression and anxiety. The first month or so was quite great. I felt an increase in motivation and life seemed to be better again. However after 2 months I'm still doing OK, but there's again this lack of enjoyment in doing things that I feel SSRI-s don't really fix very well for me in the long-term. I've tried Welbutrin add-on, but that stuff just turns me into a mess (irritable, emotional, angry etc).
Naltrexone although sounds promising. And it has been described to restore some of the effects that SSRIs lose over time (although the reports for that are rather vague and not very consistent). It would make sense that increased opioid activity results in more calmness and enjoyment in things. However I'm put off by some of its effects relating to insomnia that a lot of people report in the beginning phase of treatment with LDN. So I'm not sure whether it would work for this rather difficult aspect of depression, or, it's not worth the trouble for pursuing it for that.
SO any personal accounts with naltrexone and SSRIs would be welcomed! :) Did it do anything for your anhedonia? What would you describe as its long-term effects, the ones that persist well beyond the first weeks?
-Ikaros
poster:sk85
thread:1052317
URL: http://www.dr-bob.org/babble/20130930/msgs/1052317.html