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Re: Non-benzo PRN for sleep/anxiety

Posted by jono_in_adelaide on September 19, 2012, at 21:32:33

In reply to Re: Non-benzo PRN for sleep/anxiety » ChicagoKat, posted by brynb on September 19, 2012, at 16:31:09

There are realy only three options for sleep

Those that work through the GABA receptor (benzos, z drugs and a few oddball others)

Those that work through the histamine and seretonin receptors (most antidepressants, periactin, phenergan, sparine, atypical antipsychotics)

Those that work through the adrenalin receptors (clonidine, tianzidine, trazodone)

I often wonder wether it might be worth rotating sleep meds to prevent tolorance, taking (say) a benzo one night, Seroquel the next night, Clonidine the third night, then back to your benzo on the 4th night and so on. Theoreticaly it would make sense, I wonder if it works out well in practice?


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URL: http://www.dr-bob.org/babble/20120912/msgs/1026166.html