Posted by brynb on August 19, 2012, at 8:11:46
In reply to Re: Starting minocycline. » brynb, posted by SLS on August 17, 2012, at 15:21:14
> > Scott-
> >
> > I find this so interesting. I have an Rx for minocycline from my dermatologist (for breakouts). It's 100mg capsules. I'm thinking of adding it to my current regimen. What's the proper dosage for treating depression/inflammation?
> >
> > -b
>
> Most studies of minocycline to treat psychiatric illness have used 100 - 150 mg/day. I would start at 50 mg once per day for a few days, then 50 mg twice per day thereafter. I really don't have a "feel" for the behavior of this drug in other people yet. However, some people might be too sensitive to starting minocycline at 100 mg/day.
>
> If it turns out that I am currently experiencing the beginnings of an antidepressant response to minocycline, then it is apparent to me that some people will experience an improvement within the first week. I have seen this before with this drug. However, it is important to note that I am taking other psychotropic drugs, including Lamictal and Abilify. Lamictal, in particular, might act in concert with minocycline to disinhibit mesolimbinc dopamine release by reducing glutamate activity in the VTA. The result is increased dopamine activity. I'm sure it's not that simple, though.
>
>
> - Scott
Thanks, and I'm curious to hear how it goes for you.Also, are you in NY? I thought I saw you mention NYU in one of your posts. I started w/ a new pdoc about 2 months or so ago, and I like him (at least at the moment!), but I'm always open to new docs/clinics/etc. with expertise in mood disorders.
-b
poster:brynb
thread:1023257
URL: http://www.dr-bob.org/babble/20120818/msgs/1023655.html