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Re: Do risperdal or seroquel block autoreceptors? » poser938

Posted by SLS on October 14, 2011, at 19:41:02

In reply to Do risperdal or seroquel block autoreceptors?, posted by poser938 on October 14, 2011, at 18:47:54

> I was wondering if seroquel or risperdal block the dopamine autoreceptors like they block the postsynaptic receptors. havent been able to really find any info on the web, so if anyone cann tell me, that would be great. and if you can give me a resource that would be even better.
>
> oh and let me add, i know there is a med that blocks just the autreceptos at low doses (amisulpride) but im wondering if normal doses of reisperdal or seroquel block dopamine autoreceptors?

You might consider that all neuroleptics *increase* dopamine turnover by increasing the synthesis and release of this neurotransmitter. This is facilitated by their antagonistic action on presynaptic autoreceptors. Look for literature that describes this.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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