Posted by SLS on August 28, 2010, at 6:04:45
In reply to Re: Ad follow up of Star D Study Worse Than Before, posted by SLS on August 28, 2010, at 5:46:34
> Does anyone know what criteria were used to make one eligible to participate in the STAR*D? What was the minimum depression scored accepted?
If we are to accept Whitaker's reporting, patients were accepted whose baseline HRSD score was as low as 14. This represents mild depression. It is already established that active compounds separate from placebo by a greater amount when more severe depressions are studied. It is my belief that studies of more mild depressions include too many subjects who don't have the disorder being investigated - major depressive disorder (MDD). It is as if they were treating a bunch of people who have thrush with antibiotics. This is the wrong disease for the treatment chosen. In fact, antibiotics can make thrush worse.
- ScottThe measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:959693
URL: http://www.dr-bob.org/babble/20100821/msgs/960290.html