Posted by mtdewcmu on December 30, 2009, at 22:55:08
In reply to Zoloft and Lexapro best choices for first-line?, posted by SLS on December 30, 2009, at 8:14:17
It's interesting to notice from that paper that Remeron was the most effective antidepressant, and that it was superior in all ways to Effexor. That suggests that Remeron should be used more widely.
Another interesting thing is the fact that Lexapro came out more effective than Effexor. Doesn't that shoot holes in the whole theory that two neurotransmitters are better than one?
I have some questions about how things were measured. For instance, if a person dropped out of a study due to side effects, were they counted as a non-responder? In that case, the dropouts would be double-counted, once in the efficacy and once in the acceptability. There is no other pharmacological reason I can conceive of that Paxil rated so low in efficacy.
poster:mtdewcmu
thread:931556
URL: http://www.dr-bob.org/babble/20091227/msgs/931705.html