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Re: SSRIs in Elderly

Posted by bleauberry on December 18, 2009, at 20:53:49

In reply to Re: SSRIs in Elderly » bleauberry, posted by SLS on December 17, 2009, at 18:36:35

> It does seem that the noradrenergic drugs are effective. Unfortunately, the drugs that would probably help with late-onset depression the most - the tricyclics - are the ones that are most problematic in the elderly with respect to side effects and toxicity.
>
>
> - Scott

Actually it would seem that way. But in the case studies and small studies I recall, the TCAs were actually better tolerated than the SSRIs. The reason may be because they better suited the chemistry, or maybe because the frail and elderly did not require high doses. Low doses did the job.


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URL: http://www.dr-bob.org/babble/20091217/msgs/929873.html