Posted by garnet71 on May 23, 2009, at 21:06:22
In reply to Anxiety Meta Thread!!!, posted by garnet71 on May 23, 2009, at 20:52:18
http://www.psychosomaticmedicine.org/cgi/reprint/61/5/712
Kava is an anticonvulsant:
Kava is one of the few herbs for which active constituents are well delineated; these are the kavapyrones, including kawain, dihydrokawain, methysticin,and dihydromethysticin (59). The kavapyrones are centrally acting skeletal muscle relaxants and anticonvulsants. Their effects seem to be due to inhibition of sodium and calcium channels as well as effects on glutamate systems (69). Kava extract has been reported to affect GABAA receptors, as shown by enhanced
muscimol binding (70), but has also been reported to have no effect on GABA or benzodiazepine binding (71). Several kavapyrones, including methysticin and dihydromethysticin, are potent inhibitors of norepinephrine
uptake (72).Passionflower effective
poster:garnet71
thread:897339
URL: http://www.dr-bob.org/babble/20090515/msgs/897342.html