Posted by myco on February 21, 2009, at 12:11:46
In reply to Re: HEY SLS!! - I am profusely sorry! » desolationrower, posted by SLS on February 21, 2009, at 9:54:38
Hey,
In support of the idea of adding/combining the TCA's desipramine or nortip (even though fiercely opposed by many dr's due to supposed "absolute contraindications") I offer the following study (in support of) that shows benefit and safety in this combination (MAOI + TCA):
"Tricyclic antidepressant pharmacology and therapeutic drug interactions updated"from abstract: "The data indicate that nortriptyline and desipramine have the most pharmacologically desirable characteristics as noradrenaline reuptake inhibitors (NRIs), and as drugs with few interactions that are also safe when coadministered with either MAOIs or SSRIs."
see link for full free paper:
http://www.nature.com/bjp/journal/v151/n6/pdf/0707253a.pdf
keep smilin,
myco> I can't help but to want to recommend adding either desipramine or nortriptyline to an MAOI for treatment-resistant cases because of my continual success with this combination.
>
>
> - Scott
poster:myco
thread:880745
URL: http://www.dr-bob.org/babble/20090213/msgs/881494.html