Posted by SLS on February 19, 2009, at 15:43:42
In reply to Re: buspirone dosing » SLS, posted by iforgotmypassword on February 19, 2009, at 15:14:32
> only with extreme fatigue, pretty much.
You might be profiting from the serotonin 5-HT1a receptor partial agonism of buspirone. I guess you figured that out already. It really sucks that gepirone never made it to market.
One of the problems with buspirone is that it is extensively metabolized into 1PP. 1PP acts a lot like Remeron, a NE alpha-2 antagonist. Tandospirone does the same thing. For me, this is no good. However, for others, it might be one of the reasons buspirone has an antidepressant effect. Flesinoxan is another 5-HT1a partial agonist. It is not metabolized to 1PP. I would have liked to try that one myself.
- Scott
poster:SLS
thread:881096
URL: http://www.dr-bob.org/babble/20090213/msgs/881131.html