Posted by mav27 on November 26, 2008, at 19:32:15
In reply to Re: zoloft vs lexapro--difference in potency?, posted by bleauberry on November 26, 2008, at 19:01:58
In the same graph you can see how it takes different plasma levels to reach that 80%. zoloft only takes 25 ng/ml for 80% uptake inhibition whereas paxil takes 40 ng/ml to reach 80% uptake inhibition which is what makes the zoloft much more potent.
Prozac being one of the weaker ones takes 200 ng/ml to cause 80% reuptake inhibition.
> According to graph 3.7, 50mg Zoloft, 20mg Prozac, or 20mg Paxil have equal potency, each inhibiting the serotonin reuptake pump by 80%.
poster:mav27
thread:865220
URL: http://www.dr-bob.org/babble/20081123/msgs/865407.html