Posted by bleauberry on August 5, 2008, at 18:44:22
In STARD, what did they do with patients who were obviously getting worse on their current med trial? Were they encouraged to go the full 8 weeks, or were they terminated early and moved swiftly to the next step?
So few studies talk about the people who got worse. Lots of talk of those who did respond or didn't, but hardly any about those who got worse from a particular drug.
I've searched pubmed deeply for this info and it is scarce. Only a few studies mention it. Those that did admit that the number of people who got worse on a med is in the 5% to 15% range. It was confirmed when they returned to baseline, which was improved compared to the med, after terminating the med. But I am wondering, how did STARD approach this group of patients?
poster:bleauberry
thread:844405
URL: http://www.dr-bob.org/babble/20080805/msgs/844405.html