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antipsychotics can cause OCD sx?

Posted by iforgotmypassword on September 28, 2007, at 18:21:40

this is from wikipedia, and not flawlessly edited, but i am wondering if there is any truth to it, or if anyone else has experienced anything like it describes.

"low doses of the newer atypical antipsychotics olanzapine (Zyprexa), quetiapine (Seroquel) and risperidone (Risperdal) have also been found to be useful as adjuncts in the treatment of OCD. The use of antipsychotics in OCD must be undertaken carefully however, since although there is very strong evidence that at low doses they are beneficial (most likely due to their dopamine receptor antagonism), at high doses these same antipsychotics have proven to cause dramatic obsessive-compulsive symptoms even in those who don't normally have OCD. This is most likely due to the antagonism of 5-HT2A receptors becoming very prominent at these doses and outweighing the benefits of dopamine antagonsim."

( http://en.wikipedia.org/wiki/OCD )


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URL: http://www.dr-bob.org/babble/20070919/msgs/785786.html