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Re: Parnate at 30 mgs - still nothing » Malcolm64

Posted by Quintal on May 10, 2007, at 17:28:00

In reply to Parnate at 30 mgs - still nothing, posted by Malcolm64 on May 10, 2007, at 15:04:58

From past experience I wouldn't expect much of a response at 30mg, but sadly many psychiatrists unfamiliar with MAOIs will heed the ultra conservative advice given in their prescribing manuals. In the UK the maximum recommended dose is 30mg, doses higher than this, it warns, must be used under close supervision only, adding; usual maintenance dose 10mg daily. I've never heard of anyone using or responding to those doses in real life (though they no doubt exist).

When starting Parnate I read here that it doesn't really begin to work until the 40mg mark, and my experiences with it would support that. I can only assume the 10mg maintenance dose is recommended on the theory that Parnate works purely through MAO inhibition and that this can be maintained with a small 10mg dose. It's a flawed hypothesis IMO.

My advice would be not to expect too much until you reach the 40mg mark, and no I don't think you're whining. It's entirely normal to feel frustrated with little progress.

Q


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