Posted by madeline on December 31, 2006, at 20:22:53
In reply to Re: SSRI's and the heart » madeline, posted by linkadge on December 31, 2006, at 20:00:34
Yeah, I got that concern.
I'm just not that worried about it.
There may just not be that big of an effect in the periphery at the changes in concentration induced by the SSRI's.
Serotonin is also a vasoconstrictor in the periphery. It also may play a role in platelet aggregation and clotting.
We haven't seen changes in blood pressure, bleeding times or much along those lines in people on SSRI therapy.
I think it is a dilution issue.
Serotonin is concentrated at certain places in the brain. I think it is most likely diluted out in the periphery so a change in concentration (unless it is a big one - overdose range) probably won't matter that much.
If there are effects, they are very mild and subclinical.
poster:madeline
thread:717940
URL: http://www.dr-bob.org/babble/20061224/msgs/718032.html