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Re: Do APs block the euphoric effects of opiates?

Posted by Vale on December 17, 2006, at 7:02:42

In reply to Re: Do APs block the euphoric effects of opiates? » Vale, posted by Quintal on December 16, 2006, at 18:26:22

Hi
I know that sulperide and amisulpride are closley realted. I've swallowed enough of them to be aware of that fact. Actually the subjective effects are different from the dopamine agonists you mention.
There is a definite "neuroleptic flavour" ( for want of a better definition) about them, even at low dose.And they are prescibed throughout the dose range for negative/positive symptoms of schizophrenia.
It's true to say that drugs like Haloperidol, are distintcly dysphoric for the majority of users, (myself incl.) there are nevertheless traditional A.P's which are indicated for milder depressive states ie. Thioridazine ( I hated it though)

To get back to the original thread, Do A.P.'s block the euphoric effects of opiates?
I would hazard the answer, Yes and no,
Over the past 6 years I've been an occasional user of opium, smoked or as a tea. The euphoriant effects are by no means consistant for me, half the time when used on it's own, an actual dysphoria is evident. In order to achieve more consistancy I combine it with a low dose 25mg of Hydroxycin ( Atarax) a Piperazine, not too far removed from the classic neuroleptics. This has the effect of A/ potentiation of the Opiate euphoric effects. B/ Prolongation of those effects
C/ Reduction of the Histamine liberating side effects of Morphine. In other words a good buzz.


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poster:Vale thread:713536
URL: http://www.dr-bob.org/babble/20061217/msgs/714496.html