Posted by Larry Hoover on May 28, 2006, at 17:44:33
In reply to Re: one thing Prozac does, not chemical imbalance, posted by bassman on May 28, 2006, at 12:47:38
> One thing to note, of course, is that the study was in mice. When drugs worked in a certain way in mice (also rabbit, ferret, dog, etc.), but not in humans (which happened very frequently)-I would ask the pharmacologists that did the study why that might be. There answer was always the same, and very profound: "people aren't mice". :>}
Bang on, mate. Or the study that showed that Prozac corkscrewed neurons or receptors or whatever it was. The dose was only 110 times the human dose. Toxic threshold ring any bells?
> I wish I had a dime for every anticancer drug that has worked magnificantly in mice and didn't do anything but make people sick. Anyway, the article is interesting and sort of supports and presents a mechanism for(do you agree?) the idea that depression is a progressive disease.
Yes, it is a progressive disease, if untreated. The trick is the unleashing of the repair mechanisms. Talk therapy must do something similar, wouldn't you think? It has similar efficacy. And the combination is synergistic.
I still haven't read that full-text link. Might be something neat in there, nonetheless.
Lar
poster:Larry Hoover
thread:649281
URL: http://www.dr-bob.org/babble/20060525/msgs/649843.html