Re: Effexor metabolite submitted for FDA approval » jrbecker

Posted by ed_uk on December 23, 2005, at 15:36:05

In reply to Re: Effexor metabolite submitted for FDA approval, posted by jrbecker on December 23, 2005, at 15:18:17

Hi J
Do you know what the brand name will be?
>imipramine and desipramine
The think is, desipramine (a major metabolite of imipramine) is pharmacologically quite different to imipramine. Desipramine is a selective NRI with low affinity for other receptors eg. alpha receptors, muscarinic receptors etc. Imipramine has a high affinity for both alpha receptors and muscarinic receptors.
In contrast to this, both venlafaxine and desvenlafaxine are 'simply' serotonin and NE reuptake inhibitors with (presumably) very similar pharmacological effects.
Regards
Ed

Thread

Effexor metabolite submitted for FDA approval jrbecker 12/23/05
Re: Effexor metabolite submitted for FDA approval Sonny Liston 12/23/05
Re: Effexor metabolite submitted for FDA approval TrishP 12/23/05
Re: Effexor metabolite submitted for FDA approval jamestheyonger 12/23/05
Re: Effexor metabolite submitted for FDA approval » jamestheyonger ed_uk 12/23/05
Re: Effexor metabolite submitted for FDA approval » jrbecker ed_uk 12/23/05
Re: Effexor metabolite submitted for FDA approval » jamestheyonger Larry Hoover 12/23/05
Re: Effexor metabolite submitted for FDA approval jrbecker 12/23/05
Re: Effexor metabolite submitted for FDA approval » jrbecker ed_uk 12/23/05
Re: Effexor metabolite submitted for FDA approval » ed_uk jrbecker 12/23/05
Re: Effexor metabolite submitted for FDA approval » jrbecker ed_uk 12/23/05
Re: Effexor metabolite submitted for FDA approval linkadge 12/23/05
Re: Effexor metabolite submitted for FDA approval » linkadge Larry Hoover 12/23/05
Re: Effexor metabolite submitted for FDA approval linkadge 12/23/05
Re: Effexor metabolite submitted for FDA approval blueberry 12/23/05
Re: Effexor metabolite submitted for FDA approval » blueberry linkadge 12/23/05
Re: Effexor metabolite submitted for FDA approval » Larry Hoover ed_uk 12/23/05
Re: Effexor metabolite submitted for FDA approval jamestheyonger 12/23/05
Re: Effexor metabolite submitted for FDA approval » linkadge Phillipa 12/23/05
Re: Effexor metabolite submitted for FDA approval » ed_uk Larry Hoover 12/23/05
Re: Effexor metabolite submitted for FDA approval Sonny Liston 12/24/05
...
Re: Effexor metabolite submitted for FDA approval Sonny Liston 12/30/05

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