Posted by Chairman_MAO on October 26, 2005, at 10:53:38
In reply to Re: Anyone who had rapid cycling and got it to sto » Chairman_MAO, posted by SLS on October 26, 2005, at 8:40:28
Dopamine agonists over time drastically **REDUCE DA release** due to their actions at the autoreceptors. Their steady-state level also probably regulates the frequency, etc. of the release.
I believe that is why they are mood-stabilizing.
Due to the location of BZD receptors (im thinking of their projections through the limbic system) they are uniquely suited as antipsychotic (and antimanic, which is so obvious I do not see why I have to justify it; back in the 50s they used pentobarbital all the time for "manic psychosis" or 'manic agitation") medications--at least my neuropsych theory tells me so. Ever taken LSD and then put 10mg diazepam under the tongue? You can go from nirvana to normal in 10 minutes or less. The BZD receptors specifically inhibit ego-dissolving, overwhelming "psychotic" experiences (which I believe are correlated with excessively repetative neural firing in key areas of the brain, such as a specific region I forget where NE neurons carry sensory data elsewhere for processing. This is why NE uptake inhibitors/releasers drastically potentiate LSD trips). It is my belief that psychosis is the mind's attempt to rearrange all of reality to hide a key fact or several key facts from itself, or at least the result of its attempt to keep an ego glued together at all costs, even delusions and hallucinations.
poster:Chairman_MAO
thread:570802
URL: http://www.dr-bob.org/babble/20051024/msgs/572066.html