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SSRI zzZZZappppsss! (withdrawal)

Posted by JackD on July 25, 2005, at 21:14:55

Anyone well versed in biopsychiatry have any clue as to what receptors are responsible for the shocking withdrawal symptoms of SSRI's ( AND SNRI's)?

It's strange, because as far as I know, they "specifically" block an array of receptors, but these vary quite a bit from say Zoloft to Paxil to Lexapro. So these blocked receptors, after some time, become sensitive from having been blocked, are simply being hypersensitive and causing strange nervous system stimulus; hence shocks.

I've experienced this with Lexapro, Paxil, Zoloft and Effexor, and I know essentially any drug that has classic SSRI blockade tends to have the ZZZAAAPP effect.

Anyone have any insight? Maybe alternative explanations??

Hmmm...


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poster:JackD thread:533484
URL: http://www.dr-bob.org/babble/20050723/msgs/533484.html