Posted by ed_uk on February 16, 2005, at 7:06:14
In reply to ed- your opinion please, posted by zeugma on February 15, 2005, at 16:58:49
Hi Zeugma!
>i needed to be simultaneously calmed and stimulated
Me too!!! I don't like caffeine either, it does nothing for me, I still feel tired.
>there's clonazepam 1 mg, which keeps a lid on the anxiety but which adds to the asthenia, so i keep the dose as low as possible.
Do you think it's worth trying a different benzo? I think I've asked you that before but I don't remember what you said. You could try a low dose of chlordiazepoxide or something like that? For whatever reason, some people find certain benzos more fatiguing than others. I have a friend who found chlordiazepoxide made him more tired than clonazepam but other people seem to find the opposite.
>he wants me to retry Provigil at 50 mg tomorrow am.
Perhaps it could be worth one last try. I'm a bit concerned that what you experienced before was some kind of unusual allergic/hypersensitivity reaction. The swollen lymph nodes (lymphadenopathy) reminded me of 'serum sickness'. It's probably way off but here's a link, may drugs can cause serum sickness but I've never heard of a case with modafinil......
http://www.emedicine.com/EMERG/topic526.htm>I know it's a long shot, but I suppose it's just possible that the weird s/e I experienced on provigil were specific to nortriptyline, and that switching to desipramine might alleviate them.
It's possible, that's all I can say really. Your Provigil side effects were quite unique, I really don't know what caused them.
>And provigil, unlike d-amphetamine, would not send me to the cardiologist
I wonder whether a cardiologist might suggest bisoprolol, it's more beta1 selective than atenolol- I think it penetrates the blood brain barrier to a greater extent though.
>if it's something like akathisia, an SSRI or an AP would be a very bad idea
What makes you think it was akathisia?
Best Regards,
Ed.
poster:ed_uk
thread:446337
URL: http://www.dr-bob.org/babble/20050212/msgs/458648.html