Posted by lostforwards on October 31, 2004, at 10:58:25
Earlier I asked what's more important in depression: dopamine or serotonin? Now I'm going to rephrase what I'm asking. Do neurotrasmitter levels and receptor densities have an impact on a persons personality? And if that's true, then wouldn't taking one type of antidepressant over another have different impacts on the person who takes it's personality and whether they actually become who they were before..or someone else.
I'm suspicious because of various things I've read about people being transformed into different people taking SSRIs. Everybody's heard of the book listening to prozac right?
On top of that, the things I've read about people who are sex addicts or obsesive compulsive makes me wonder what feeding the world SSRIs preferentially as antidepressants might have on us all.
I know that dopamine neurons are found primarily in the frontal lobes. I also read stuff about amotivational syndrome being associated with SSRIs in different places and I've become more curious.
now.. I find this:
http://www.lycaeum.org/drugs/SSRI/balance.html
...while there's no citation of any sort, and I'm not sure of the validity of the information.."..According to this hypothesis, typical SSRIs would INCREASE this ratio and thus, preferentially, stimulate those 5-HT receptors which decrease dopamine neurotransmission while atypical SSRIs would, preferentially, stimulate 5-HT2A receptors and so stimulate dopamine neurotransmission..."
Does that mean people who take SSRIs lower activity in their frontal lobes? Is that where amotivational syndrome comes frome?
poster:lostforwards
thread:409540
URL: http://www.dr-bob.org/babble/20041029/msgs/409540.html