Posted by Ritch on October 23, 2004, at 11:44:53
In reply to PLEASE HELP., posted by ravenstorm on October 23, 2004, at 9:51:42
> How could I be fine on 200mg WB and 15mg remeron, screw around with the doses and get worse anxiety so return to where I was EXCEPT even less WB (only 100mg) and still be crawling out of my skin. The anxiety is totally destabilizing me. HELP. I am feeling like this is the end of the line for me. I just wanted to limp through the winter on the remeron and WB until spring and re-evaluate. I can't be like this with the days getting shorter. I can't make it through another winter like this. I had a somewhat normal life for four weeks out of a whole year. I can't go through this again.
I read that history of meds and the thing that stands out is dropping a serotonergic (Paxil) and the presence of Wellbutrin. I've had similar experiences with Wellbutrin. While at small doses it works OK short-term (a few days) to pick my energy level back up.. I find over weeks that my anxiety starts to worsen a LOT. Wellbutrin has several metabolites that tend to accumulate over time so that the ratio of the parent drug to the metabolites is reduced quite a bit-I think those metabolites are very anxiogenic. Another thing I found is that while Remeron worked well for my panic symptoms and sleep, it made me really agitated and restless.. kind of like taking a bunch of yohimbine and Benadryl together. In short it sounds like you and Wellbutrin don't mix well and adding Remeron to it isn't helping. It might be best to cut the Wellbutrin drastically to see if the anxiety lifts, or stop it for one day and see if you feel a lot better. It sounds like the WB is the root of the problem.
poster:Ritch
thread:406164
URL: http://www.dr-bob.org/babble/20041018/msgs/406358.html