Posted by linkadge on February 12, 2004, at 10:20:29
In reply to Buspar mechanism of action, posted by chess on February 11, 2004, at 10:58:13
Serotonin at the 5ht1a receptor decreases anxiety while serotonin at the 5ht2a receptor can cause anxiety.
Buspar tries to acitvate the 5ht1a receptor and decrease serotonin, thereby reducing the serotonin at the 2a receptor.
SSRI's activate all receptors. They activate the 1a receptor which can decrease anxiety but they also activate the 2a receptor which can cause initial anxiety till the system adjusts.
As you can see it is not an exact science.
But those are the basics of it.
Linkadge
poster:linkadge
thread:312027
URL: http://www.dr-bob.org/babble/20040210/msgs/312418.html