Posted by ace on December 9, 2003, at 19:30:18
In reply to NARDIL QUESTION - ACE, posted by falconman on December 9, 2003, at 8:24:17
> Hi mate,
>'Mate'? Are you an Aussie too!! It's good to hear, with all the 'yanks' on this site!!!
How has Nardil/Amisulpride mix effected you?
No real effect yet. I feel confident but. I have been on 50mg for only 1 week 3 days. I'll give it a month- I'm sure it will kick in before that though. I let you know when it kicks in!
Can you briefly explain the 'prolactin problem'with zyprexa/amisulpride?Yeah sure. As you probably know both Amisulpride and Zyprexa both on their own raise prolactin levels. So when combine this will be more so. A high serum level concentration of prolactin can lead to potency, headaches, visual problems and more. I really don't think that there is too much chance of this however. Just monitor the two and all should be cool.
> My Pdoc said when I reach the highest tolerable dose of Nardil he'd add zyprexa. I'm on 60mg of Nardil/day.
I believe you should raise to 90mg after 4 weeks on 60mg. Also, I would keep Zyprexa at 2.5mg, no higher- this is my experience though. At higher than 2.5mg it felt like it worked against Nardil and cause me a bad depression.
I've been on it for 6 weeks and the side effects are pretty bad- Very low blood pressure,I've never has this really.
cognitive dysfunction(worst,I can't remember words for things etc.)
Had this BIG TIME for a short while- it passed though.
,Shakey limbs
Had a bit. Passed but.,can't exersize,
I never really exercise anyway!!
disorientated,Had this for a while too- it passed.
water retention,didn;t really have it I think.
constipation,
Yeah, got this right now. It does pass but does take quite some time usually. Eat bran.
not to mention my little man doesn't work but I fully expected that one.Dude, I know about that! Mine has just died recently after 9 weeks or so back on Nardil. I thought I had made it, but my penis just had to go on me!!!!!!!!!!! Can't believe it!!
When I begun it was much worse than now, butI seem to have stabalized at this point(which isn't great). This is very annoying
Please be patient. Nardil s/effects nearly all pass. Just time, sweet time.
cause it is helping the depression,social phobia,depersonalization a little bit. I wish I could get more down me, but this is the most I will get out of nardil.For the moment. Give it a bit more time for the s/effects to pass, then I recommend raising dosage again.
>
> I'm seeing my Pdoc tommorrow and its time to augment. I'm a bit weary of zyprexa, I don't want any more side effects + won't it actually reduce dopamine/seratonin levels?Probably not at 2.5mg that I'm aware off- but, yeah, I wouldn't be too confident at the moment with this. Why not try...
1 Amisulpride? (DA added activity completely)
2. Lithium? (5HT added activity mostly)
2. Pindolol? (5HT added activity mostly)
3. Trazadone? ( reckon this would be great with Nardil) (5HT added activity mostly)
I know I need a dopamine hit so I'm going to push for the amisulpride instead.Good idea!! Remeber there is Mirapex too. Too bad this is not in Australia- I would probably give it a go.
> I wish I could get more nardil in me man
> peace MarkPeace to you brother. I reckon give the Nardil some more time to lett s/eefects pass- believe me most do- just for some they take a while.
good luck!
Ace.
poster:ace
thread:287976
URL: http://www.dr-bob.org/babble/20031208/msgs/288130.html