Posted by david maclean on July 17, 2003, at 19:29:34
How does a psych doc go about selecting an MAOI for atypical (apathetic) depression?
I have hard that Nardil is sedating and that Parnate is energising. Is that the main criterion for choosing between these two?
The UK pharms guide for docs (the BNF) says this ... "Tranylcypromine (Parnate) is the most hazardous of the MAOIs because of its stimulant action. The drugs of choice are phenelzine (Nardil) or isocarboxazid (Marplan) which are less stimulant and therefore safer."
Have they got it right? In what way do they mean that Parnate is dangerous on account of its stimulant action?
What about Marplan (Isocarboxazid)? I don't hear much about this one. Is this because it is usually a very last choice?
Is the preferred choice Nardil then Parnate then Marplan?
I would welcome any info on the questions I have asked. Thank you.
poster:david maclean
thread:242996
URL: http://www.dr-bob.org/babble/20030714/msgs/242996.html