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Mifepristone question » Pfinstegg

Posted by Frog on April 7, 2003, at 12:28:41

In reply to Re: cortisol is the consequence of my problems » Frog, posted by Pfinstegg on April 6, 2003, at 17:26:12

Dear Pfinstegg ,

Regarding Marsilid , yes it increases the levels of all three neurotransmitters- serotonin, norepinephrine and dopamine.
The good thing at the moment is that I don't have any side effect at all , with my past experience with other antidepressant suchs as Prozac, Effexor, Seroxat, Ixel, Anafranil : I was always having at least one side effect.

>I am under the impression that Mifepristone is much more readily available in Europe than it is here- and has been used more often for Cushing's >Disease.

In your previous message , I thought you were saying that a new antidepressant will be released based on Mifepristone molecule , but I just realised that is in fact mefipristone itself that has been used as an antidepressant and have shown dramatical result. And yes , I can confirm that this pill is available here(France), this pill is also known as RU-486 or "abortion pill".

> You could be said to have "pseudo-Cushing's Syndrome". Even though the cause is not a tumor, the drug treatment would be the same. I would >really try to choose that one over ketanozodole, as you always have to worry about your liver function with ketanozodole, and mefipristone has >such a good safety profile.

Regarding Cushin's Syndrome , I thought of that idea when I see I got high levels of cortisol (after 24h urine test).I am about to do another cortisol test on Wednesday at 08:00 am (cortisol reaches its peak at this time) but result could not be so exact since I am on Marsilid.

About mifepristone pill , I am really interested in this pill but I am also sceptic for my situation , I read that depressed people who tried Mifepristone had to follow this treatment with conventional antidepressant(after Mifepristone relieves depression) for having a consolidation of their state.
So , if I have well understand , Mifepristone can lower dramatically cortisol levels and it because those cortisol levels are lowered(and therefore become normal)that conventionnal antidepressant can make positive effect.
Would it mean that all antidepressant that I took in the past could work well on me after having a Mifepristone treatment ?

>I do wish you the very best in getting into a full remission- and hope you will keep us informed about what treatments you decide upon.

Thanks for your support , as I said above , it is today my 5th day on Marsilid 50mg , no side effect at all , Maoi Diet is fine too , well I just need to wait....

Frog.


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