Posted by djmmm on April 5, 2003, at 18:07:14
In reply to Re: Parnate - is it serotonin agonist, posted by Caleb462 on April 3, 2003, at 22:02:39
> > YES! It ihibits the Monoamine oxidace that oxidizes the amino acids serotonin, norepinephrine, and to a smaller extent dopamine. It is NOT an agonist, that is the wrong terminology. An agonist is like Cocaine, for example, which directly mimics dopamine and is therefore a D1 (dopamine suptype 1) agonist cause it stimulates it DIRECTLY. MAOI's don't directly stimulate anything, they just allow your neurotransmitter levels to rise.
>
> Well, you are also mistaken. Cocaine is not a D1 agonist. It is a reuptake inhibitor of Dopamine, Norepinephrine, and Serotonin.
>
>There is some evidence that MAOIs act as indirect agonists of catecholamines...I haven't read anything about MAOIs being serotonin agonists.
poster:djmmm
thread:215621
URL: http://www.dr-bob.org/babble/20030402/msgs/216506.html