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Re: benzo's reducing dopimine transmission?

Posted by cybercafe on March 19, 2003, at 23:57:57

In reply to Re: benzo's reducing dopimine transmission?, posted by djmmm on March 18, 2003, at 15:24:20

> Activation of the GABA(A) system, and supression of the adenylyl cyclase cyclic AMP pathway by Klonopin causes the decrease in dopamine transmission. Most Anticonvulsants manipulate dopamine in some way (Klonopin, tegretol, zonegran, Neurontin, etc.)
>
>

hmmm.... can you clarify something for me? i read somewhere that D2-D4 receptors reduced adenylyl cyclase turnover ... does that mean they have an inhibitory effect?


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