Posted by Ritch on June 6, 2002, at 23:18:29
In reply to Re: Trimipramine » Ritch, posted by Chloe on June 6, 2002, at 22:34:00
> Mitch,
> Thanks for the links. I did some searches on Google too. Not a ton of info on this particular TCA...That I can find (in my messed up state). But hopefully I am starting to come out of this mood.
>
> I did send a email to the pdoc about Trimip. I basically outlined what you said. I am not really hopeful that she will go for this change. I wonder if she is familiar with Trimip...
> Geez, I hope at least she answers me! That would be decent and helpful.
>
> Thanks a million
> Chloe
Chloe,I went to www.mentalhealth.com and went into their research topics (Medline) through the drug monograph. It seems like it was used (as doxepin was) to treat ulcers back in the '70's and '80's before the modern H2 antagonists were available. What it appears to me after reading a lot of the stuff about it is that it may not be as potent an antidepresant as other TCA's are, but doesn't hose up sleep architecture like other TCA's can and still has some antidepressant effect and helps sleep. One study I checked into showed that it tends to reduce cortisol similar to AP's, without other major changes in other hormone levels (that caught my attention). So, perhaps you might not get as irritable as on amitrip.? However, you are partly using the amitrip. for neuropathic pain, and I didn't see any studies on neuropathic pain. Oh, well.
Mitch
poster:Ritch
thread:108844
URL: http://www.dr-bob.org/babble/20020602/msgs/109013.html