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Re: selegiline stuff » Jason911

Posted by Elizabeth on February 22, 2002, at 23:09:10

In reply to Re: selegiline stuff, posted by Jason911 on February 22, 2002, at 15:38:36

Hi again. I'm not sure that deprenyl will be any better for the anxiety than Wellbutrin is, but I think it's worth a try. I found selegiline very jittery, but I was taking a high (nonselective) dose. If you're just taking 5-10 mg, you don't need to watch your diet, and it will probably cause less anxiety than I experienced. Don't expect miracles, mind you, but as I said, I think it's worth trying. (Note: it doesn't have the magical anxiolytic power of Nardil.)

I found Wellbutrin to be jittery as well, even at lower doses than you're taking. It wasn't a pleasant activated antidepressant feeling (and I took it for a full month) with improved mood, motivation, pleasure, concentration, etc. -- instead it was an unpleasant wired feeling, like what you might get from taking too much Sudafed. (I once tried Nicorette -- I'm a non-smoker -- and that was sort of what WB felt like.)

> I got word last night that he wanted me to take 1mg in the morning .5mg at noon and 1mg before bed. Is it best to separate them??? Because I only get the effect on at least 2mg at once!

I think that you should try the schedule your pdoc suggested for a few days. You might find it quite effective. I found that taking my dose (4 mg/day) in 3 divided doses made things smoother.

> This pisses me off. He increases Wellbutrin, and he is so adament about the fact that that is THE drig of choice when it comes to Dopamine-related depression.

The evidence that Wellbutrin has any effect on dopamine is very sketchy. And the evidence that any particular person's depression has to do with dopamine is nonexistent. Why do you believe your depression is "dopamine-related?"

(As I mentioned, the mechanism of action of Wellbutrin is unknown. It appears to involve dopamine -- that is, there is some evidence that *suggests* this -- but this is far from established.)

-elizabeth


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URL: http://www.dr-bob.org/babble/20020222/msgs/95175.html