Posted by manowar on December 8, 2001, at 17:43:36
In reply to Re: What AD next? Please help if you can, posted by Jenna S. on December 7, 2001, at 18:52:27
>
> > I’ve read that prefrontal cortex functioning heavily affects mood. I don’t know if the dose of Concerta is enough to normalize cortical functioning. Maybe I need to add a dose of Modafinil or Adrafinil? Any suggestions?
>
> Would you consider an atypical antipsychotic? I have read that they improve prefrontal cortex functioning. I've taken Zyprexa and Risperdal and found that they gave me a greater clarity of thought. I don't take them now because of side effects and worries about potential side effects. I believe the improvement in the prefrontal cortex occurs because antagonism of 5HT2A receptors somehow increases dopamine there. It would be nice if there was a drug that just blocked those receptors and nothing else. I don't need or want dopamine blocking as well.Thanks Jenna,
Yes I have tried one anti-psychotic. I started Seroquel about three weeks ago. I kinda felt a bit of cognitive impairment and I felt even more depressed as usual. After stopping the Seroquel, I still felt more depressed than usual and I determined that the Adderal that I started one week prior to the Seroquel was the culprit.
I stopped the Adderal a few days ago, and I feel a little better.
I also started taking Neurontin a few days ago. So far, it seems that I get the same side effects that I did with the Seroquel (e.g. cognitive impairment, a little dizzy when standing).
If I don't do well on the Neurontin, I'll keep the Seroquel or another anti-psychotic in mind.
I know this is stupid but what is the 5HT2A receptor?
Thanks for your support,
Tim
poster:manowar
thread:86080
URL: http://www.dr-bob.org/babble/20011202/msgs/86331.html