Posted by SalArmy4me on July 30, 2001, at 23:36:18
In reply to Re: How to NOT gain weight on zyprexa???? » JohnL, posted by Zo on July 25, 2001, at 19:40:18
Topiramate:
The American Journal of Psychiatry. Volume 156(6) June 1999 pp 968-969 Mood Stabilization and Weight Loss With Topiramate
"...In these patients, the substitution of topiramate for valproate resulted in significant weight loss. Mr. A, with bipolar disorder, experienced no loss of thymoleptic efficacy; Ms. B, with unipolar depression and impulsivity, experienced increasing depression and anxiety. Anxiety has been reported as an adverse effect of topiramate [1]. Like other thymoleptic anticonvulsants, topiramate has significant effects on gamma-aminobytyric acid function [2], but the mechanism of its effects on weight is unknown. Further study should clarify topiramate's utility in treating mood disorders."
ALAN GORDON, M.D.
LAWRENCE H. PRICE, M.D.
Providence, R.I.
poster:SalArmy4me
thread:71683
URL: http://www.dr-bob.org/babble/20010725/msgs/72638.html