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Is half-life the whole story?

Posted by JohnM on March 9, 2001, at 18:58:01

In reply to Re: Please suggest a long-acting benzodiazepine, posted by jb on March 9, 2001, at 15:53:30

I seem to find contradictions with half-life of a med and its duration of effect in the CNS. For example compare Ativan to Valium. Ativan, although it has a much shorter half life, supposedly has a longer duration of effect than Valium.

From a nursing pharmacology book I looked at, it seems that Tranxene (clorazepate) or Serax (oxazepam) would be my best bet.


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poster:JohnM thread:55579
URL: http://www.dr-bob.org/babble/20010302/msgs/56058.html