Posted by JohnX on March 7, 2001, at 4:27:43
In reply to Please suggest a long-acting benzodiazepine, posted by JohnM on March 4, 2001, at 19:30:29
> I need to know what would be the next longest acting benzodiazepine after Klonopin. Although I can get by on very low doses of benzos (for social anxiety/phobia) the problem I have with them is that my body "metabolizes" (if that's the word) them very quickly. Xanax, Ativan, and Valium all worked well for me, but I needed to take another dose after about 2 hours with Xanax and Ativan and about 3 hours with Valium. I've used Klonopin and it lasted 5 hours which I felt was "reasonable", but I felt it had a sort of "depressing" effect on me (I know Klonopin is often indicated for its anti-convulsant and anti-manic properties)--maybe that has something to do with it.
>
> I would appreciate some information on other possibilities. From my own research, I came to the conclusion that Serax (oxazepam) would be the next choice. Your suggestion? JohnDo you remember if the inserts to Xanax,Ativan,
or Valium contraindicated taking them with
graprefruit juice or cemitidine (Tagamet)?I seem to recall these meds being
deaminated (broken down) in the liver by an enyme
that is inhibited by one of the two. I could
dig up the drug interactions if you are interested.It will be playing with fire, but possibly you can
drink a small amount of grape fruit juice to increase the 1/2 life (decrease metabolization) of the med. Anyone scream at me for suggesting this.Have you tried SSRI anti-depressant medications
like Paxil? I took benzos and hit the addiction
wall. I'll tell you it's pretty heinous when this happens.-John
poster:JohnX
thread:55579
URL: http://www.dr-bob.org/babble/20010302/msgs/55816.html