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What does down regulation mean?

Posted by PhoenixGirl on January 30, 2001, at 15:28:44

I've read that ADs can "down regulate" neurotransmitter receptors. Desipramine, for example, is said to "down regulate" 5H2 serotonin receptors. What does that mean, and is it permanent? What effect does it have on people?


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poster:PhoenixGirl thread:52975
URL: http://www.dr-bob.org/babble/20010122/msgs/52975.html